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| The study of the relationship between senile degenerative heart valvular disease and coronary artery disease |
| CHU Hong-gang1, YU Bang-mei2, GUO Rui-qiang1, SUN Bin1, JIANG Xia1, SUN You-gang1 |
| 1.Department of Ultrasound, Renmin Hospital, Wuhan University, Wuhan 430060, China;2.Service Department of Family Planning of Jingzhou, Jingzhou Hubei 434000, China |
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Abstract Objective: To determine whether there is an relation between senile degenerative heart valvular disease(SDHVD) with coronary artery disease(CAD) in subjects age≤65 years old. Methods: The age of the 298 patients were ≤65 years old. All patients underwent transthoracic echocardiography and coronary arteriography at the same time. Results: ①There was a progressive increase incidence of hypertension(P<0.001) and diabetes(P<0.05) with an increasing rate of calcium deposits of SDHVD as increase in age(P<0.001). ②With an increasing sites with calcium deposits of SDHVD, there was a progressive increase in positive results of coronary arteriography(P<0.001). ③Multiple logistic analyses identified SDHVD as significant predictors for the positive prevalence of coronary arteriography(P<0.01). In female patients and age ≤55 years, SDHVD was statistically significant predictors of the positive prevalence of coronary arteriography(P<0.001, P<0.05, respectively). Conclusions: There is a significant relation between SDHVD and coronary artery disease. The presence of SDHVD is an independent predictor of coronary artery disease.
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Received: 20 June 2006
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2007, Vol. 18 
