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| Quantitative evaluation of left ventricular myocardial systolic dyssynchrony in patients with heart failure by TVI, SI, SRI and RT-3DE |
| LI Yu-feng1, REN Wei-dong1, JI Ri1, ZHOU Jie-ying1, YAN Hua2, CHEN Xin1, CHENG Yan-bin1 |
| 1. Cardiovascular Test Department, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;2. Dazhong Hospital of Shenyang, Shenyang 110031, China |
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Abstract Objective: To evaluate left ventricular myocardial systolic dyssynchrony in patients with heart failure(HF) by tissue velocity imaging(TVI), strain rate imaging(SRI), strain imaging(SI) and real-time three-dimensional echocardiography(RT-3DE). Methods: Fifty-seven subjects were divided into two groups. Group A consisted of 27 normal subjects, and group B included 30 patients with HF. Patients in group B were divided into three subgroups according to LVEF and two subgroups on the basis of QRS width. The former consisted of mild(6), moderate(18) and severe(6) HF patients, and the latter included narrow QRS subgroup(22) and wide one(8). Tissue Doppler imaging(TDI) and full volume were performed with Philips IE33. The times to the point of peak velocity(Tv), strain rate(Tsr), strain(Ts) during systolic phase, to the point of minimal volume(Tmv) and cardiac cycle were obtained by the on-line Qlab software. The LVEF was derived from RT-3DE. Results: LV systolic dyssynchrony in patients with HF was evaluated by TVI, SRI, SI and RT-3DE. There was significant difference in normal subjects, mild, moderate and severe HF patients(P<0.05). Curves in group A arranged orderly by TVI, SRI, SI, and RT-3DE, while that in group B ranked disorderly. There was no significant difference of SDI between wide QRS subgroup and narrow one. Significant negative correlation existed between LVEF and SDI, where RT-3DE and TVI appeared better than SRI and SI. Conclusion: All the TVI, SRI, SI and RT-3DE can evaluate LV systolic dyssynchrony noninvasively and quantitatively, but RT-3DE can provide a novel, quick and convenient technique.
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Received: 08 May 2007
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2007, Vol. 18 
