To evaluate the left ventricular mechanics changes in patients with acute heart failure after#br# treatment by rhBNP using two-dimensional speckle tracking imaging
Department of Ultrasound, People’s Hospital of Hunan Province, Changsha 410000, China
Abstract：Objective: To investigate the left ventricular twist in patients with acute heart failure after treatment by rhBNP using two-dimensional speckle tracking imaging． Methods: Forty cases of acute heart failure patients were given conventional therapy. Respectively, in the application of the rhBNP before and after treatment, the left ventricular mechanics parameters were obtainted, the parameters included peak apical rotation(Par), peak basal rotation(Pbr), peak twist(Ptw）, peak untwist velocity(PutwV), time to peak twist（TPK). The above data of another 40 healthy volunteers were measured as control. Results: Compared with control group, Par, Pbr, Ptw and PutwV of patients with acute heart failure all obviously decreased before treatment by rhBNP(all P<0.001) among them, Par relatively obvious decline compared Pbr, the twist parameters improved in some degrees after treatment by rhBNP, but were still lower compared to those of control group(all P<0.05). Conclusion: rhBNP treatment can effectively improve the left ventricular function in patients with acute heart failure, 2D-STI can assess left ventricular myocardiac mechanics changes after rhBNP treatment quantitatively and objectively, and provide an effective and noninvasive method for clinical evaluation of left ventricular function．
李慎义，陈红天，龙湘党，刘 亮. 二维斑点追踪显像技术在评价急性心力衰竭患者#br# 新活素治疗后左心室扭转之变化[J]. 中国临床医学影像杂志, 2015, 26(11): 791-793.
LI Shen-yi, CHEN Hong-tian, LONG Xiang-dang, LIU Liang. To evaluate the left ventricular mechanics changes in patients with acute heart failure after#br# treatment by rhBNP using two-dimensional speckle tracking imaging. JOURNAL OF CHINA MEDICAL IMAGING, 2015, 26(11): 791-793.
[1]李朝军，谢明星，王新房，等. 超声斑点追踪显像技术Logistic回归和ROC曲线联合评价慢性心功能不全患者心肌扭转的改变[J]. 中华超声影像学杂志，2007，16（12）：1026-1030.
[2]Puwanant S, Park M, Popovic ZB, et al. Ventricular geometry,strain, and rotational mechanics in pulmonary hypertension[J]. Circulation, 2010, 121(2): 259-266.
[3]Blessberger H, Binder T. Non-invasive imaging: two dimensional speckle tracking echocardiography: basic principles[J]． Heart, 2010, 96(9): 716-722.
[4]Chang SA, Kim HK, Kim DH, et al. Left ventricular twist mechanies in patients with apical hypertrophic cardiomyopathy: assessment with 2D speckle tracking echocardiography[J]. Heart, 2010, 96(1): 49-55.
[5]董瑞庆. 斑点追踪显像技术评价慢性心力衰竭患者左心室扭转及解旋运动的临床研究[D]. 苏州：苏州大学，2011.
[6]Kim HK, Sohn DW, Choi SY, et al. Assessment of left ventricular rotation and torsion with two-dimensional speckle tracking echocardiography[J]. J Am Soc Echocardiogr, 2007, 20(1): 45-53.
[7]Bansal M, Leano RL, Marwick TH. Clinical assessment of left ventricular systolic torsion: effects of myocardial infarction and ischemia[J]. J Am Soc Echocardiogr, 2008, 21(8): 887-894.
[8]Moravi V, Lang RM, Badano LP, et al. Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endosed by the Japanese Society of Echocardiography[J]. J Am Soc Echocardiogr, 2011, 12(3): 167-205．
