中国临床医学影像杂志
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结直肠原发神经内分泌癌的CT表现
李振辉,张治平,董兴祥,杨光军,高德培,张大福
昆明医科大学第三附属医院 云南省肿瘤医院放射科,云南 昆明  650118
CT features of colorectal neuroendocrine carcinomas
LI Zhen-hui, ZHANG Zhi-ping, DONG Xing-xiang, YANG Guang-jun, GAO De-pei, ZHANG Da-fu
Department of Radiology, the Third Hospital of Kunming Medical University,
Tumor Hospital of Yunnan Province, Kunming 650118, China
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摘要 目的:探讨结直肠原发神经内分泌癌(NECs)的CT征象,以提高结直肠原发NECs的术前诊断。方法:回顾性分析经病理确诊的32例原发性结直肠NECs患者和46例结直肠腺癌患者的CT表现,比较两组患者发病年龄、性别、肿瘤发生部位、病变大小、肠壁增厚形式、平扫、增强CT值、肠周浸润情况、有无肠梗阻及其他器官转移等的差异。结果:与结直肠腺癌组比较,结直肠原发NECs组患者发病年龄小(t=3.634,P<0.001),两组在肠壁增厚形式、病灶大小、病灶强化程度等方面差异有统计学意义(P<0.05),在性别、病灶发生部位、有无肠梗阻、有无区域淋巴结转移、有远处转移等方面差异无统计学意义(P>0.05)。结论:结直肠NECs发病年龄较轻,其CT表现为息肉/肿块样病灶,密度均匀,增强动脉期表现为中度或显著强化,静脉期进一步强化时,应考虑到结直肠NECs的可能,并可出现显著强化的肝脏转移病灶。
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李振辉
张治平
董兴祥
杨光军
高德培
张大福
关键词 结直肠肿瘤;内分泌腺肿瘤;体层摄影术螺旋计算机    
Abstract:Objective: To explore the CT findings of primary colorectal neuroendocrine carcinomas(NECs), and to improve the imaging diagnosis of them. Methods: CT findings of 32 patients with primary colorectal NECs and 46 patients with colorectal adenocarcinoma confirmed by surgery and pathology were analyzed retrospectively. The differences of age, gender, tumor location, size of the lesion, the thickening pattern of the intestinal wall, the pattern of contrast-enhancement, the peri-intestinal invasion, the occurrence of intestinal obstruction and metastasis to other organs were compared between the two groups. Results: Compared with the colorectal adenocarcinoma group, patient of colorectal NECs group was younger(t=3.634, P<0.001). There were statistically significant differences of focal thickening, size of the lesion and contrast-enhancement(P<0.05). While in gender, lesion location, occurrence of intestinal obstruction, lymph node metastasis, or metastasis, there was no statistically significant difference(P>0.05). Conclusion: Primary colorectal NECs are often found in young patients. Their CT manifestations include a polypoid lesion and is characterized by significant contrast-enhancement. Significantly contrast-enhanced metastasis may occur in liver.
Key wordsColorectal neoplasms    Endocrine gland neoplasms    Tomography, spiral computed
收稿日期: 2016-09-27     
PACS:  R735.35  
  R735.37  
  R730.264  
  R814.42  
基金资助:云南省科技厅-昆明医科大学应用基础研究联合专项基金(基金编号:2014FB062)。
通讯作者: 张大福,昆明医科大学第三附属医院 云南省肿瘤医院放射科,650118。E-mail:tosney@126.com   
作者简介: 李振辉(1986-),男,河南平舆人,医师。E-mail:lizhenhui621@qq.com
引用本文:   
李振辉,张治平,董兴祥,杨光军,高德培,张大福. 结直肠原发神经内分泌癌的CT表现[J]. 中国临床医学影像杂志, 2017, 28(6): 430-433.
LI Zhen-hui, ZHANG Zhi-ping, DONG Xing-xiang, YANG Guang-jun, GAO De-pei, ZHANG Da-fu. CT features of colorectal neuroendocrine carcinomas. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(6): 430-433.
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