摘要目的：应用多普勒超声心动图监测经胸放疗期间左室舒张功能的变化。方法：36例经胸放射治疗的患者，进行两次多普勒超声心动图检查，首诊检查：放射治疗前1~3天；复诊检查：放射治疗结束当天。测量舒张期二尖瓣口血流频谱及二尖瓣环运动频谱的两峰比值（E/A，e/a）。结果：舒张期二尖瓣口血流频谱及二尖瓣环运动频谱的两峰值比率均显示，两次测量结果间存在显著性差异（E/A：0.77±0.19 vs 0.69±0.13， e/a：0.82±0.31 vs 0.75±0.19，均P<0.05）。结论：经胸放疗期间左室舒张功能受损，多普勒超声心动图可及时作出诊断。
Abstract：Objective: To investigate the variation of left ventricular diastolic function during thoracic radiation treatment using Doppler echocardiography. Methods: The study group consisted of 36 patients with thoracic radiotherapy. The patients were examined twice, the first examination: 1~3 days before the radiation treatment; the second examination: the day of radiation treatment was finished. Doppler echocardiographic examinations were performed by measuring the ratio of two peaks of mitral inflow Doppler velocity and mitral annular diastolic velocity profile(E/A, e/a). Results: E/A and e/a between two examinations were significantly different(E/A: 0.77±0.19 vs 0.69±0.13, e/a: 0.82±0.31 vs 0.75±0.19, both P<0.05). Conclusion: Left ventricular diastolic function was damaged during thoracic radiation treatment, which can be diagnosed by Doppler echocardiography in time.
2008, Vol. 19 
