Abstract:Objective: To study the character of extrahepatic collateral arterial supply of primary hepatic carcinoma and its interventional therapy. Methods: 343 patients with primary hepatic carcinoma who underwent transcatheter arterial chemoembolization for many times were retrospectively analyzed. The interventional therapy of transcatheter arterial chemoembolization was performed by selective catheterization or superselective catheterization in the patients with extrahepatic collateral arteries. Results: A total of 83 extrahepatic collateral arteries were found in 73 patients. The incidence was 20.7%(71/343). They originated from right inferior phrenic artery(41.0%), gastroduodenal and epiploic artery(18.1%), right adrenal artery or subcapsular artery(12.1%), cystic artery(8.4%), right intercostal artery(6.0%), superior mesenteric artery(4.8%), lumbar artery(3.6%), left gastric artery(3.6%), and right internal mammary artery(2.4%), respectively. The successful rate of super selective catheterization of extrahepatic collateral arteries was 92.8%(77/83). The transcatheter arterial chemoembolization or arterial embolization with lipiodol was performed in the arteries of successful catheterization. Conclusions: It is necessary to determine the existence of extrahepatic collateral arterial supply and perform the super selective transcatheter arterial embolization in primary hepatic carcinoma with repeated TACE, which is clinically significant to improve the efficacy of interventional therapy.