Abstract：Objective: To improve the understanding of imaging and pathologic findings of hepatic epithelioid hemangioendothelioma(EHE). Methods: The clinical imaging findings of four cases with hepatic EHE were retrospectively analyzed. All cases were confirmed by biopsy or surgical pathology. Three cases underwent plain and contrast-enhanced CT scans, one case underwent CT and MRI examination. Results: CT images showed single or multiple quasi-circular hypodense lesions, clear boundary, progressive mild enhancement, no enhancement in the central area． MRI images showed multiple ring shaped nodules in liver, the essence of the lesions had slightly longer T1 and T2 relaxation times and ring-shaped continued enhancement, the central of the lesions had slightly short T1 relaxation times and very long T2 relaxation times, no enhancement. Histology results revealed proliferation of abnormal fibrous tissue which were scattered with epithelioid cells and signet ring-like structure． By immunohistochemical staining, all cases were positive for CD34, CD31 and factor Ⅷ-related antigen． Conclusion: The imaging findings of hepatic EHE has certain characteristics, which manifested as single or multiple lesions, the lesion can be mutual confluence and located in the subcapsular, together with “capsular retraction sign”．Enhanced scan showed progressive enhancement, together with “lollipop sign”.
2015, Vol. 26 
