Abstract：Objective: To study the imaging and pathological features of the primary orbital non-Hodgkin’s lymphoma. Methods: It was a retrospective case series study. Nine patients with the primary orbital non-Hodgkin’s lymphoma were surgically treated in our hospital from January 2008 to December 2014, and had been pathologically confirmed. All patients were performed with ultrasonography, 8 cases with CT, 7 cases with MRI, in which 4 cases with enhanced MRI, 1 case with 18F-FDG PET/CT scan. The data of imaging and pathology were retrospectively analyzed. Results: The inner ball and optic nerve were not invading in all cases. The lesions in 5 of 9 cases located in both of intra- and extra-conal space, and mainly in extraconal one. An intra- and extra-conal involvement of each case. Five cases of lesions involved mainly in peribulbar, 3 cases located behind the ball and 1 case in the eyelid of the ball, destruction of orbital bone was evident in 1 case with diffuse lesions. In 7 of 9 with ultrasonography were considered as occupying or mass, uniform density of soft-tissue mass with local infiltration shaped edges were showed on plain CT film in 6 cases. The signal intensity of the lesions was equal or slightly long T1, T2 homogeneous signal intensity, similar to the extraocular muscles, homogeneous enhancement in enhanced MR scan, intracranial invasion was prompted by the bone destructive lesion. The patient who was performed with postoperative PET/CT, the metabolism of 18F-FDG increased as SUVmax=2.4 in the eyelid, suggesting the lesion residue. According to the new WHO classification of lymphoma: 5 cases of B cell of mucosa-associated lymphoid tissue lymphoma(MALT), each one of diffuse large B-cell lymphoma(DLBCL), follicular lymphoma(FBL), T-cell lymphoblastoid lymphoma(T-LBL) and nature killer/T cell lymphoma(NK/T). Conclusion: The imaging(ultrasound, CT and MRI) of the primary orbital non-Hodgkin’s lymphoma is characteristic, the efficacy of lymphoma surgery can be evaluated by PET/CT, highly aggressive type of malignant pathology with strong invasiveness, the accuracy rate of diagnosis relying solely on imaging is low, the combination of pathology and immunohistochemistry still be required.
王 超;王晓明. 眶内原发非霍奇金淋巴瘤的影像学特征及病理学分析[J]. , 2015, 26(8): 542-547.
WANG Chao;WANG Xiao-ming. Imaging features and pathological analysis of the primary orbital non-Hodgkin’s lymphoma. , 2015, 26(8): 542-547.
2015, Vol. 26 
