99mTc-MIBI核素显像与CT在原发性甲状旁腺功能亢进症中的诊断价值

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摘要目的：通过对术前99mTc-甲氧异腈（MIBI）核素显像与CT图像分析，探讨分析两者在原发性甲状旁腺功能亢进症中的临床诊断价值。方法：回顾分析经病理证实的38例原发性甲状旁腺功能亢进症患者术前99mTc-MIBI核素显像和CT影像资料，比较99mTc-MIBI核素显像、CT、99mTc-MIBI核素显像与CT联合3种影像学方法对原发性甲状旁腺功能亢进症的诊断灵敏度差异。结果：99mTc-MIBI核素显像、CT、99mTc-MIBI核素显像与CT联合3种影像学方法诊断原发性甲状旁腺功能亢进症的灵敏度分别为89.65%、64.00%、93.75%；统计分析显示99mTc-MIBI核素显像组与CT组、CT组与联合组之间差异有统计学意义，99mTc-MIBI核素显像与CT联合组灵敏度优于其它两种方法。结论：术前99mTc-MIBI核素显像与CT对原发性甲状旁腺功能亢进症的评估均是必要的，两者联合应用可提高原发性甲状旁腺功能亢进症的诊断价值。

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	陈正国
	刘启榆
	陈娇
	杨兴
	何瑜

关键词 ：甲状旁腺功能亢进症；99m锝甲氧基异丁基异腈；放射性核素显像；体层摄影术, X线计算机

Abstract：Objective: To explore the clinical value of 99mTc-sestamibi(MIBI) scintigraphy and CT in the diagnosis of primary hyperparathyroidism. Methods: Retrospectively analyzed the image features of 99mTc-MIBI and CT in 38 patients with primary hyperparathyroidism, which were confirmed by pathology. Comparison of the sensitivity of 99mTc-MIBI scintigraphy, CT, the combination of the two methods. Results: The sensitivity of 99mTc-MIBI, CT and the combined methods in diagnosis of primary hyperparathyroidism was 89.65%, 64.00% and 93.75% respectively. There were significant difference between 99mTc-MIBI and CT, CT and the combination group. The sensitivity of the combination group was superior to the other two methods. Conclusion: Both 99mTc-MIBI and CT provide important information for the pre-operation evaluation of primary hyperparathyroidism. 99mTc-MIBI in combination with CT can increase the accuracy of diagnosis of the primary hyperparathyroidism.

Key words： Hyperparathyroidism Technetium Tc 99m sestamibi Radionuclide imaging Tomography, X-ray computed

收稿日期: 2015-08-24

PACS:	Ｒ582.1
	Ｒ817.4
	Ｒ814.42

通讯作者: 陈正国，绵阳市中心医院放射科，621000。E-mail：maiwang342@163.com

作者简介: 陈正国（1976-），男，四川绵竹人，主治医师。E-mail：maiwang342@163.com

引用本文:

陈正国，刘启榆，陈娇，杨兴，何瑜. 99mTc-MIBI核素显像与CT在原发性甲状旁腺功能亢进症中的诊断价值[J]. 中国临床医学影像杂志, 2016, 27(4): 239-242.
CHEN Zheng-guo, LIU Qi-yu, CHEN Jiao, YANG Xing, HE Yu. The diagnostic value of 99mTc-sestamibi scintigraphy and CT in primary hyperparathyroidism. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(4): 239-242.

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http://www.jccmi.com.cn/CN/ 或 http://www.jccmi.com.cn/CN/Y2016/V27/I4/239

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