摘要目的：探讨宫颈鳞癌血流灌注指标血管指数（Vascularization index，VI）与病理分级及微血管密度（Microvascular density，MVD）的相关性。方法：57例宫颈鳞癌患者，采用三维彩色血管能量成像技术（Three-dimensional color power angiography，3D-CPA）在术前对癌组织内血管进行三维重建，将其与病理分级及MVD值进行分析。结果：57例宫颈鳞癌患者VI与MVD呈正相关（r=0.612，P＜0.05），术后各病理组织学分级Ⅰ～Ⅲ级与VI、MVD比较，差异有统计学意义（P＜0.05），随病理组织学分级的增高，VI、MVD亦增高。结论：VI与宫颈鳞癌病理分级及MVD呈正相关，3D-CPA能够在术前对肿瘤血供进行定量分析，为临床医生术前评估宫颈鳞癌分级提供有力证据。
Abstract：Objective: To explore the correlation of perfusion index vascularization index(VI), pathological grading and microvascular density(MVD) cervical squamous cell carcinoma. Methods: Fifty-seven cases of cervical squamous cell carcinoma patients, three-dimensional color power angiography(3D-CPA) was used for reconstruction of blood vessels within cancerous tissue in the preoperative patients, and analyzed pathological grade and MVD value. Result: There was positively correlation between VI and MVD(r=0.612, P<0.05) in the 57 cases with cervical squamous cell carcinoma. There was statistically significant difference among them by comparing pathological grade Ⅰ~Ⅲ with VI and MVD(P<0.05), and with value of the VI, MVD had increased, the pathology grade would be high. Conclusions: It was positively correlated VI, histological grade and MVD in patients with cervical squamous cell. 3D-CPA may provide quantitative analysis for clinical doctor, and assess the grade of cervical squamous cell before surgery clinicians.
张红彬，栗河舟，郝志伟，郭丽亚. 宫颈鳞癌三维彩色血管定量与病理分级及微血管密度的相关性研究[J]. 中国临床医学影像杂志, 2016, 27(8): 570-572.
ZHANG Hong-bin, LI He-zhou, HAO Zhi-wei, GUO Li-ya. Correlation of cervical squamous cell carcinoma vascular quantitative three-dimensional color and pathological grading and micro-vessel density. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(8): 570-572.
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