Abstract：Objective: To explore the application value of virtual touch tissue quantification(VTQ) in the differential diagnosis of benign and malignant thyroid nodules. Methods: One hundred and thirteen patients with 147 thyroid nodules undergoing thyroid nodules surgery or biopsies after thyroid nodules VTQ examination were retrospectively reviewed. The shears wave velocity(Vs) was measured. The patients were selected from our hospital during Feb. 2013 to Jul. 2015. All cases were divided into benign nodules group(n=52) and malignant nodules group(n=95), according to the pathological results. The Vs of the two groups were detected and statistically analyzed. The ROC curve was drawn, and finally the critical point distinguishing the benign and malignant thyroid nodules Vs was defined. Results: In the 147 focuses, there were 52 benign nodules with the average Vs(2.36±0.44), while 95 malignant nodules with the average Vs(3.65±0.81). There were statistical differences between them(P<0.01). The ROC curve was drawn according to the SWV of the benign malignant nodule. The area under the curve was 0.92±0.02. After analysis, it was concluded that the critical point of the benign and malignant thyroid nodules SWV was 2.96. The corresponding sensitivity, specificity, accuracy, PPV and NPV were 85.3%, 88.5%, 86.4%, 93.1% and 76.7%. Conclusion: VTQ can be regarded as the differential diagnosis basis for benign and malignant thyroid nodules, and has some application value in clinical diagnosis.
费正东，谢卫峰，曹 磊，姜 慧，王红慧，崔红燕. 声触诊组织定量技术（VTQ）在甲状腺良恶性结节鉴别诊断中的#br#
应用价值[J]. 中国临床医学影像杂志, 2016, 27(9): 612-615.
FEI Zheng-dong, XIE Wei-feng, CAO Lei, JIANG Hui, WANG Hong-hui, CUI Hong-yan. Application value of virtual touch tissue quantification in the differential diagnosis of benign and#br#
malignant thyroid nodules. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(9): 612-615.
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2016, Vol. 27 
