颅骨腺泡状软组织肉瘤的影像学表现

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摘要目的：探讨颅骨腺泡状软组织肉瘤（Alveolar soft part sarcoma，ASPS）的影像学特征。资料与方法：回顾性分析8例经手术病理证实的颅骨ASPS的CT（n=8）、MRI（n=8）及MR静脉造影（MRV）（n=2）表现。结果：8例ASPS均以推压头皮软组织向外生长为主，向内则与硬脑膜分界不清。CT表现：6例原发性APSP呈溶骨性骨质破坏，见不均匀密度肿块，含斑片状残留骨质，边缘示不完整骨性薄壳；2例继发性ASPS呈溶骨性骨质破坏，肿块密度较均匀。MRI表现：6例原发性ASPS外观呈“蘑菇征”，呈以等T1、长T2、高DWI信号为主的混杂信号，内部可见片状T2WI高信号（n=6）、点条状低信号（n=4）或簇状血管影（n=2），MR增强示明显不均匀强化，并于肿瘤两侧出现“硬膜尾征”；2例继发性ASPS呈卵圆形，呈均匀等T1、等T2信号，明显均匀强化；6例原发性ASPS的ADC值平均为2.19×10-4 mm2/s，2例继发性ASPS的ADC值平均为1.76×10-4 mm2/s。MRV表现：上矢状窦受压，肿块内见大量引流静脉。结论：颅骨ASPS具有特征性的影像表现，结合其临床、病理特征，有助于本病的诊断。
?眼关键词?演肉瘤，软组织腺泡状；颅骨肿瘤；体层摄影术，螺旋计算机；磁共振成像；磁共振血管造影术

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	李洋
	郝大鹏
	石祥龙
	于俪媛
	万光耀
	刘吉华
	徐文坚

关键词 ：肉瘤, 软组织腺泡状, 颅骨肿瘤, 体层摄影术, 螺旋计算机, 磁共振成像, 磁共振血管造影术

Abstract：Objective: To investigate the imaging features of alveolar soft part sarcoma(ASPS) in skull. Materials and Methods: The CT and MRI of eight patients with ASPS in skull confirmed by pathology were analyzed retrospectively. Results: All patients were shown excentric growth with pushing the scalp soft tissue and unclear margins abutting upon duramater. On CT scanning, six primary ASPSs were shown soft tissue mass with heterogeneous density, in which contained residual bone and uncompleted bony shell(n=6). The bone destruction was mainly osteolytic destruction(n=6). Two secondary ASPSs were shown soft tissue mass with homogeneous density and osteolytic destruction(n=2). On MRI scanning, six primary ASPSs were shown mushroom sign(n=6). The tumors appeared as hyper-intensity on T2WI, iso-intensity on T1WI and hyper-intensity on DWI(n=6). There were patchy hyper intensity areas, punctual/stripy hypo-intensity areas(n=4), clustered vessel signals(n=2) in tumors on T2WI. Inhomogeneous enhancement was seen on contrast-enhanced scan in six cases. Dural tail sign was seen in both side of the tumor(n=6). Two secondary ASPSs were shown orbicular-ovate mass(n=2). The tumors appeared as iso-intensity on T2WI and iso-intensity on T1WI(n=2). Homogeneous enhancement was seen on contrast-enhanced scan in two cases. The mean ADC value of six primary ASPSs was 2.19×10-4 mm2/s. The mean ADC value of two secondary ASPSs was 1.76×10-4 mm2/s. MRV was shown superior sagittal sinus pushed with a large number of drainage veins in the tumors. Conclusion: ASPS in skull was shown some typical imaging features. Combination the imaging features, clinical findings and pathology are helpful to the diagnosis the disease.

Key words： Sarcoma, alveolar soft part Skull neoplasms Tomography, spiral computed Magnetic resonance imaging Magnetic resonance angiography

收稿日期: 2015-11-10

PACS:	Ｒ738.6
	Ｒ739.41
	Ｒ814.42
	Ｒ445.2

通讯作者: 郝大鹏，青岛大学附属医院放射科，266003。Email：haodp_2009@163.com

作者简介: 李洋（1988-），男，山东青岛人，在读硕士研究生。E-mail：ly8848128@126.com

引用本文:

李洋，郝大鹏，石祥龙，于俪媛，万光耀，刘吉华，徐文坚. 颅骨腺泡状软组织肉瘤的影像学表现[J]. 中国临床医学影像杂志, 2016, 27(8): 584-588.
LI Yang, HAO Da-peng, SHI Xiang-long, YU Li-yuan, WAN Guang-yao, LIU Ji-hua, XU Wen-jian. The imaging manifestations of alveolar soft part sarcoma in skull. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(8): 584-588.

链接本文:

http://www.jccmi.com.cn/CN/ 或 http://www.jccmi.com.cn/CN/Y2016/V27/I8/584

[1]Wang HW, Qin XJ, Yang WJ, et al. Alveolar soft part sarcoma of the oral and maxillofacial region: clinical analysis in a series of 18 patients[J]. Oral Pathol Oral Radiol, 2015, 119(4): 396-401.
[2]Portera CA Jr, Ho V, Patel SR, et al. Alveolar soft part sarcoma: clinical course and patterns of metastasis in 70 patients treated at a single institution[J]. Cancer, 2001, 91(3): 585-591.
[3]Feng M, Jiang W, He Y, et al. Primary alveolar soft part sarcoma of the uterine cervix: a case report and literature review[J]. Int J Clin Exp Pathol, 2014, 7(11): 8223-8226.
[4]Folpe AL, Deyrup AT. Alveolar soft-part sarcoma: a review and update[J]. J Clin Pathol, 2006, 59(11): 1127-1132.
[5]McCarville MB, Muzzafar S, Kao SC, et al. Imaging features of alveolar soft-part sarcoma: a report from Children’s Oncology Group Study ARST0332[J]. AJR, 2014, 203(6): 1345-1352.
[6]Schenning R, Vajtai P, Troxell M, et al. Alveolar soft part sarcoma: unusual etiology of mediastinal mass in an adolescent[J]. Clin Pract, 2013, 3(2): e26.
[7]Anbarasi K, Sathasivasubramanian S, Kuruvilla S, et al. Alveolar soft-part sarcoma of tongue[J]. Indian J Pathol Microbiol, 2011, 54(3): 581-583.
[8]Cohen DB, Jones DM, Fergus AH, et al. Metastatic alveolar soft-part sarcoma of the intracranial skull base: case report[J]. Skull Base, 2002, 12(1): 33-38.
[9]Kinger M, Chakrabarti P, Varma A, et al. Alveolar soft part sarcoma of tongue in 14-year-old boy[J]. Ann Maxillofac Surg, 2014, 4(2): 240-242.
[10]Nakano H. Alveolar soft part sarcoma: histogenesis[J]. Anticancer Res, 1998, 18(6A): 4207-4211.
[11]Christopherson WM, Foote FW, Stewart FW. Alveolar soft-part sarcomas; structurally characteristic tumors of uncertain histogenesis[J]. Cancer, 1952, 5(1): 100-111.
[12]刘亿，漆松涛. “脑膜瘤硬尾征”与脑膜瘤部位及其病理类型的关系[J]. 中国临床神经外科杂志，2012，28（5）：499-503.
[13]周正荣，王坚，彭卫军，等. 腺泡状软组织肉瘤的影像学特征及临床病理表现[J]. 中国癌症杂志，2009，19（1）：12-16.
[14]Kim HS, Lee HK, Weon YC, et al. Alveolar soft-part sarcoma of the head and neck: clinical and imaging features in five cases[J]. AJNR, 2005, 26(6): 1331-1335.
[15]张海栋，王仁法，万捷，等. 腺泡状软组织肉瘤的MRI表现[J]. 放射学实践，2009，24（9）：1033-1036.
[16]张碧云，黄海青，陈自谦. 原发性颅骨内脑膜瘤的CT与MRI表现[J]. 中国临床医学影像杂志，2009，20（7）：549-550.
[17]解中福，靳松，阎晓玲，等. 颅骨骨化性纤维瘤的CT、MRI表现与组织病理学相关性分析[J]. 实用放射学杂志，2009，25（7）：947-950.