Abstract：Objective: To investigate the clinical value of 18F-FDG PET/CT puncture site selection for multiple lung lesions. Method: A retrospective analysis of 164 patients with multiple lung lesions was performed, including 60 patients with preoperative 18F-FDG PET/CT guided core needle biopsy and the rest 104 patients with contrast-enhanced CT guided biopsy. Results: Among the 60 patients with 18F-FDG PET/CT guided core needle biopsy, fifty-nine had definite pathological diagnosis. The rates of technical success in acquiring samples was 98.3%, with 57 biopsy sites in the area of maximum SUV. In 104 patients contrast-enhanced CT guided biopsy, eighty-six had definite pathological diagnosis, the rate of technical success in acquiring samples was 82.7%. Difference of the two data sets was statistically significant(χ2=7.63, P＜0.05). Conclusions: Compared to CT-guided biopsy, 18F-FDG PET/CT has higher diagnostic accuracy in selecting SUVmax areas in lesions as the puncture site.
杨 超，丘建燊，张 芨，雷 娟，张鸿文. 18F-FDG PET/CT在肺内多发病灶穿刺部位选择中的临床价值[J]. 中国临床医学影像杂志, 2017, 28(1): 30-34.
YANG Chao, QIU Jian-rong, ZHANG Ji, LEI Juan, ZHANG Hong-wen. Clinical value of 18F-FDG PET/CT in puncture site selection for multiple lung lesions. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(1): 30-34.
[1]张鸿文，张芨，雷娟，等. CT引导下经皮肺穿刺活检在管外型中央型肺癌中的诊断价值[J]. 临床肺科杂志，2012，17（5）：886-888.
[2]李天然，陈自谦，郑春雨. 临床PET/CT诊断学[M]. 北京：人民卫生出版社，2008：236-237.
[3]Higashi K, Ito K, Hiramatsu Y, et al． F-FDG uptake by primary tumor as a predictor of intratumoral lymphatic vessel invasion and lymph node involve mentin non-small cell lung cancer: analysis of a multicenter study[J]． J Nucl Med, 2005, 46(3): 267-273．
[4]Ohtsuka T, Nomori H, Watanabe K, et al. Prognostic significance of F-FDG uorodeoxy glucose uptake on positron emission tomography in patients with pathologic stage I lung adenocarcinoma[J]． Cancer, 2006, 107(2): 2468-2473．
[5]Berghmans T, Dusart M, Paesmans M, et al． Primary tumor standardized uptake value(SUVmax) measured on fluorodeoxyghcoze positron emission tomography(FDG-PET) is of prognostic value for surviva in non-small cell lung cancer(NSCLC): a systematic review and meta-analysis(MA) by the European Lung Cancer Working Party for the IASLC Lung Cancer Staging Pmjeet[J]． J Thomc Oncol, 2008, 3(2): 6-12．
[6]Hellwig D, Greeter rip, Ukena D, et al． F-FDG PET formediastinal staging of lung cancer: which SUV threshold makes sense?[J]. J Nucl Med, 2007, 48(5): 1761-1766．
[7]张鸿文，陶超超，张芨，等. PET-CT选择肺内多发病灶再穿刺病灶的价值[J]. 临床肺科杂志，2015，20（5）：795-798.
[8]叶永青，赵祥玲，林承奎，等. CT引导下经皮肺穿刺活检在肺部占位性病变诊断中的诊断价值[J]. 临床肺科杂志，2013，18（2）：233-235.
[9]Lardinois D, Weder W, Hany TF, et al. Staging of non small cell lung cancer with integrated positron emission tomography and computed tomography[J]. N Engl J Med, 2003, 348(25): 2500-2507.
[10]YooIe R, Chung SK, Park HL, et al. Prognostic value of SUVmax and metabolic tumor volume on 18F-FDG PET/CT in early stage non-small cell lung cancer patients without LN metastasis[J]. Biomed Mater Eng, 2014, 24(6): 3091-3103.
[11]Nguyen XC, Nguyen VK, Tran MT, et al. Prognostic Value of Fluoro-D-glucose Uptake of Primary Tumor and Metastatic Lesions in Advanced Nonsmall Cell Lung Cancer[J]. World J Nucl Med, 2014, 13(2): 112-119.
[12]O’Dowd EL, Kumaran M, Anwar S, et al. Brain metastases following radical surgical treatment of non-small cell lung cancer: Is preoperative brain imaging important[J]. Lung Cancer, 2014, 86(2): 185-189.
2017, Vol. 28 
