Abstract：Objective: The aim of this study was to assess the correlation of maximum standardized uptake values(SUVmax) and minimum apparent diffusion coefficient(ADCmin) with pathological grade respectively, and assess the quantitative relationship between SUVmax and DWI ADC values in rectal adenocarcinoma. Methods: Preoperative PET/CT and pelvic MRI imaging of thirty-five patients with rectal adenocarcinoma were retrospectively analysed. After measurement of SUVmax and ADCmin, correlation analysis was conducted. Results: The mean SUVmax were significantly different among groups classified by histologic differentiation grades. The differences of mean SUVmax among T-stage groups were not significant(P>0.05). Tukey’s post hoc test showed statistical differences of mean SUVmax between well and moderately differentiated groups, well and poorly differentiated groups(P<0.05). The ADCmin was significantly different when comparing groups classified by histologic differentiation grade and T stage. The mean ADCmin of different groups differed significantly with each other(P<0.05). In the T-stage groups, only the mean ADCmin of stage T4 tumor was significantly different from that of each the other three T stages(P<0.05). A significantly negative correlation was found between SUVmax and ADCmin(r=-0.540; P<0.05). Conclusion: SUVmax and ADCmin values can reflect pathologic features of rectal cancer. The significantly negative correlations between SUVmax and ADCmin suggest an association between tumor cellularity and metabolic activity in rectal adenocarcinoma.
高晶晶，李绍东，代 岳，徐慧婷，王 琪. 直肠腺癌18F-FDG PET/CT SUV与磁共振表观弥散系数相关性分析[J]. 中国临床医学影像杂志, 2017, 28(1): 55-59.
GAO Jing-jing, LI Shao-dong, DAI Yue, XU Hui-ting, WANG Qi. Correlation of standardized uptake value on fluorodeoxyglucose PET/CT with apparent diffusion coefficient#br# in patients with rectal adenocarcinoma. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(1): 55-59.
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2017, Vol. 28 
