肝纤维化影像学研究进展

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摘要肝纤维化是多种慢性肝病向肝硬化进展的核心病理过程。早期、定量及精准诊断对肝纤维化的预防意义重大。由于肝穿活检的局限性，影像学检查成为评价肝纤维化的重要手段，尤其是近年来，以弹性成像为代表的功能成像及分子成像技术飞速发展，已经在一定程度上取代病理检查，肝脏穿刺活检率逐年下降。因此，本文将就肝纤维化的影像学检查研究现状与进展作一述评。

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	郭启勇
	石喻
	王威

关键词 ：肝硬化, 磁共振成像

Abstract：Liver fibrosis is the core pathological process in various chronic liver diseases. Early detection, quantitative and accurate diagnosis are of great significance for the prevention of hepatic fibrosis. Because of the limitations of liver biopsy, imaging examination has become an important method to evaluate hepatic fibrosis. In recent years, functional imaging represented by elastography and molecular imaging have developed rapidly and have replaced pathological examination to a certain extent. The rate of liver biopsy decreased year by year. Therefore, this article will review the current status and progress of imaging studies of hepatic fibrosis.

Key words： Liver cirrhosis Magnetic resonance imaging

收稿日期: 2017-07-11

PACS:	Ｒ575.2
	Ｒ445.2

基金资助:国家自然科学基金青年科学基金项目（编号81401376；编号81471718；编号81271566）；中国医科大学国家自然科学基金优秀青年科学基金培育项目（编号YQ20160005）。

通讯作者: 郭启勇，中国医科大学附属盛京医院放射科，110004。E-mail：guoqiyongcmu@163.com

作者简介: 郭启勇（1958-），男，浙江东阳人，教授。E-mail：guoqiyongcmu@163.com

引用本文:

郭启勇，石喻，王威. 肝纤维化影像学研究进展[J]. 中国临床医学影像杂志, 2017, 28(10): 685-691.
GUO Qi-yong, SHI Yu, WANG Wei. Advances in imaging study of liver fibrosis. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(10): 685-691.

链接本文:

http://www.jccmi.com.cn/CN/ 或 http://www.jccmi.com.cn/CN/Y2017/V28/I10/685

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