Abstract:Objective: To evaluate the ability of first-trimester placental volume and vascular indices to predict small-for-gestational-age(SGA) birth weight pregnancies. Methods: Retrospective comparative analysis placental volume, multiples of median(MOM), Doppler vascular index in 242 single pregnancy at 11~13 weeks+6 without complications, fetal malformations in our hospital between appropriate-for-gestational-age(AGA) and SGA at delivery. Results: The placental volume and MOM in the SGA group were significantly lower than those in the AGA group(AGA 74.32±20.28, SGA 51.57±11.65, P=0.008; AGA 1.00±0.05, SGA 0.93±0.04, P=0.004). There were no significant differences in vascular indices, including vascularization index(VI), blood flow index(FI) and vascularized blood flow index(VFI)(VI: P=0.602, FI: P=0.561, VFI: P=0.490). Conclusions: The placenta volume measured by three-dimensional ultrasonography in 11~13 weeks+6 can predict SGA, while the vascular indices have little effect on SGA.
董秀娟,张 丽. 孕早期胎盘体积和血管指数对小于胎龄儿的预测[J]. 中国临床医学影像杂志, 2017, 28(11): 822-824.
DONG Xiu-juan, ZHANG Li. First-trimester placental volume and vascular indices in the prediction of small-for-gestational-age neonates. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(11): 822-824.
[1]Cheong KB, Leung KY, Chan HY, et al. Comparison of inter- and intra-observer agreement between three types of fetal volume measurement technique(XI VOCAL, VOCAL and multiplanar)[J]. Ultrasound Obstet Gynecol, 2009, 33(3): 287-294.
[2]Lee W, Kalache KD, Chaiworapongsa T, et al. Three-dimensional power Doppler ultrasonography during pregnancy[J]. J Ultrasound Med, 2003, 22(1): 91-97.
[3]李玲,李宁,张艳卿,等. 不同喂养方式对早产小于胎龄儿生长发育影响的研究[J]. 中国儿童保健杂志,2014,22(2):146-148.
[4]钟鑫琪,崔其亮. 早产儿和小于胎龄儿发生的危险因素的比较分析[J]. 中国当代儿科杂志,2014,12(8):1202-1205.
[5]汪浩文,陈红霞,吴超华,等. 不同营养方式对小于胎龄儿生长发育影响的临床对照研究[J]. 中国儿童保健杂志,2010,18(9):649-651.
[6]Karagiannis G, Akolekar R, Sarquis R, et al. Prediction of small-for-gestation neonates from biophysical and biochemical markers at 11-13 weeks[J]. Fetal Diagn Ther, 2011, 29(2): 148-154.
[7]Effendi M, Demers S, Giguere Y, et al. Association between first-trimester placental volume and birth weight[J]. Placenta, 2014, 35(2): 99-102.
[8]Plasencia W, Akolekar R, Dagklis T, et al. Placental volume at 11-13 weeks’ gestation in the prediction of birth weight percentile[J]. Fetal Diagn Ther, 2011, 30(1): 23-28.
[9]鲁嘉,戴晴,孟华,等. 孕11~13+6周三维超声测量胎盘体积与新生儿出生体重及胎盘重量和体积的相关性[J]. 中华医学超声杂志,2015,12(2):142-147.
[10]de Paula CF, Ruano R, Campos JA, et al. Placental volumes measured by 3-dimensional ultrasonography in normal pregnancies from 12 to 40 weeks’ gestation[J]. J Ultrasound Med, 2008, 27(11): 1583-1590.
[11]Pairleitner H, Steiner H, Hasenoehrl G, et al. Three-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization[J]. Ultrasound Obstet Gynecol, 1999, 14(2): 139-143.
[12]Rosner M, Dar P, Reimers LL, et al. First-trimester 3D power Doppler of the uteroplacental circulation space and fetal growth restriction[J]. Am J Obstet Gynecol, 2014, 211(5): 521-528.