Abstract：Objective: To determine the CT findings of otosclerosis and evaluate the value of high resolution CT in the diagnosis of otosclerosis. Materials and Methods: 25 patients with confirmed diagnosed by clinical and surgical examination were collected from December 2015 to March 2018 at the First Affiliated Hospital of China Medical University. 20 patients with confirmed non-otosclerosis sclerosis were collected at the same time. The patients were examined by high resolution CT before operation. Results: A total of 35 ears were found abnormal in 20 patients(40 ears) after CT examination, with the sensitivity of 87.5%, and specificity of 80%. 22 ears were the vestibular window type(62.9%), mainly represented as the enlargement or narrowing of the vestibular window and the thickening of the stapes foot plate on CT. 9 ears were the cochlear window type(25.7%), mainly represented as the low density of the bones around the cochlea on CT. 4 ears were the mixed type (11.4%), mainly represented as the low density and the destruction of the bones in labyrinth on CT. Conclusion: Otosclerosis could be diagnosed on high-resolution CT with high sensitivity and specificity. High resolution CT can identify the site and extent of otosclerosis, and can effectively identify the lesions and determine the type, providing important information for preoperative assessment and surgical plan.
吴权洋，郑瑞宾，王嘉奇，李松柏. 耳硬化症的临床与影像分析[J]. 中国临床医学影像杂志, 2019, 30(5): 309-312.
WU Quan-yang, ZHENG Rui-bin, WANG Jia-qi, LI Song-bai. Clinical and imaging analysis of otosclerosis. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(5): 309-312.
[1]Karosi T. Correlation of Computed Tomography with Histopathology in Otosclerosis[J]. Otol Neurotol, 2013, 34(7): 1362-1363.
[2]Naumann IC, Porcellini B, Fisch U. Otosclerosis: incidence of positive findings on high-resolution computed tomography and their correlation to audiological test data[J]. Ann Otol Rhinol Laryngol, 2005, 114(9): 709-716.
[3]Valvassori GE. Imaging of otosclerosis[J]. Otolaryngol Clin North Am, 1993, 26(3): 359-371.
[4]Veillon F, Stierle JL, Dussaix J, et al. Otosclerosis imaging: matching clinical and imaging date[J]. J Radiol, 2006, 87(11 Pt 2): 1756-1764.
[5]Linthicum FH Jr. Histopathology of otosclerosis[J]. Otolaryngol Clin North Am, 1993, 26(3): 335-352.
[6]吴红莲，高献芳，梁长虎，等. 耳硬化症的高分辨率CT诊断[J]. 医学影像学杂志，2016，26（1）：22-24.
[7]Tringali S, Pouget JF, Bertholon P, et al. Value of temporal bone density measurements in otosclerosis patients with normal-appearing computed tomographic scan[J]. Ann Otol Rhinol Laryngol, 2007, 116(3): 195-198.
[8]Sziklai I, Batta TJ, Karosi T. Otosclerosis: an organ-specific inflammatory disease with sensorineural hearing loss[J]. Eur Arch Otorhinolaryngol, 2009, 266(11): 1711-1718.
[9]Lagleyre S, Sorrentino T, Calmels MN, et al. Reliability of high-resolution CT scan in diagnosis of otosclerosis[J]. Otol Neurotol, 2009, 30(8): 1152-1159.
[10]Shin YJ, Fraysse B, Deguine O, et al. Sensorineural hearing loss and otosclerosis: a clinical and radiologic survey of 437 cases[J]. Acta Otolaryngol, 2001, 121(2): 200-204.
[11]Swartz JD, Faerber EN, Wolfson RJ, et al. Fenestral otosclerosis: significance of preoperative CT evaluation[J]. Radiology, 1984, 151(3): 703-707.
[12]Kawase S, Naganawa S, Sone M, et al. Relationship between CT densitometry with a slice thickness of 0.5 mm and audiometry in otosclerosis[J]. Eur Radiol, 2006, 16(6): 1367-1373.
[13]Purohit B, Hermans R, Op de Beeck K. Imaging in otosclerosis: a pictorial review[J]. Insights Imaging, 2014, 5(2): 245-252.
[14]Vicente Ade O, Yamashita HK, Albernaz PL, et al. Computed tomography in the diagnosis of otosclerosis[J]. Otolaryngol Head Neck Surg, 2006, 134(4): 685-692.
[15]Swartz JD. The otodystrophies: diagnosis and differential diagnosis[J]. Semin Ultrasound CT MR, 2004, 25(4): 305-318.
[16]Diaz RC. Cochlear otosclerosis[J]. Otol Neurotol, 2008, 29(5): 723-724.
[17]王晓茜，吴佩娜，许咪咪，等. 耳硬化CT表现与临床症状的比较分析[J]. 中华耳科学杂志，2011，9（2）：153-155.
[18]徐卫星. 高分辨率CT（HRCT）骨密度测量法在耳硬化症中的诊断价值[J]. 中国CT和MRI杂志，2016，14（4）:11-13.
[19]Ukkola-Pons E, Ayache D, Pons Y, et al. Window Niche Height: Quantitative Evaluation with CT before Stapes Surgery for Otosclerosis[J]. AJNR, 2013, 34(5): 1082-1085.
[20]Lee TC, Aviv RI, Chen JM, et al. CT Grading of Otosclerosis[J]. AJNR, 2009, 30(7): 1435-1439.
2019, Vol. 30 
