Abstract：Objective: To investigate the value of Revolution CT perfusion imaging in differentiating adrenal lipid-poor adenoma(adenoma in short) and adrenal metastases of lung cancer(metastases in short). Materials and Methods: The data of adrenal Revolution CT perfusion scanning in our hospital were retrospectively collected, 13 cases of adenoma(CT value >10 HU) were pathologically confirmed, and 7 cases and 10 lesions of metastases were confirmed by clinical history and follow-up imaging. The size, unenhanced and enhanced CT attenuation numbers and perfusion parameter measurements(blood flow(BF), blood volume(BV), mean transit time(MTT), time to peak(TP) and permeability of surface(PS)) of tumors were recorded. Comparison of the above parameters between adenomas and metastases was tested. Receiver operating characteristic(ROC) curves were plotted to analyze diagnostic efficiency. Results: There was not statistical difference of length, minimum width, unenhanced CT value and enhanced CT values between adenoma and metastases group(all P>0.05). BF and BV values of adenoma were statistically higher than those of metastases(66.32±50.33 vs. (34.21±34.99) mL/(100 g·min), 18.81±5.93 vs. (8.06±5.44) mL/100 g, P=0.005 and 0.001, respectively), while there was not statistical difference of MTT, TP and PS values between the two tumors(P all>0.05). The area under the ROC curve of BF and BV values were 0.875 and 0.923, and there were a sensitivity of 92.3% and 75.0%, and a specificity of 84.6% and 100% for differentiating adenoma from metastases. Conclusion: It is difficult to identify adrenal lipid-poor adenoma and adrenal metastases of lung cancer by routine CT examination. However, BF and BV values can be used to identify both of them for higher diagnostic efficacy.
赵 莹，刘爱连，刘静红，刘义军，王 楠，方 鑫. Revolution CT灌注成像对肾上腺乏脂性腺瘤与
肺癌肾上腺转移瘤的鉴别价值[J]. 中国临床医学影像杂志, 2018, 29(11): 792-797.
ZHAO Ying, LIU Ai-lian, LIU Jing-hong, LIU Yi-jun, WANG Nan, FANG Xin. Value of Revolution CT perfusion imaging in differentiating adrenal lipid-poor adenoma and
adrenal metastases of lung cancer. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(11): 792-797.
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