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| Prenatal ultrasonographic diagnosis of fetal right isomerism syndrome |
| LI Xue-lei, MU Zhong-ping, HUANG Ting |
Maternal and Child Health Care Hospital Affiliated to Medical University of Anhui, Department of Ultrasound,
Anhui Province Maternal and Child Health Hospital, Hefei 230001, China |
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Abstract Objective: To investigate the prenatal ultrasonographic features of the right isomerism syndrome and to improve its prenatal detection rate. Methods: Ultrasonographic features of 11 cases of fetal isomerism in our hospital from April 2015 to May 2017 was analyzed. Results: In 11 cases of right isomerism syndrome, there were 10 cases of malposition of chest and abdominal organs(10/11). In 6 cases, the space between the gastric bubble and the spinal column was narrow, showing an adjacent relationship(6/11). Eleven cases were complicated with heart malformations and venous anomalies. Eight cases had pulmonary venous abnormalities, including 4 cases of the formation of the common pulmonary vein draining into the right atrium. Three cases had extracardiac malformations, including cleft lip, hiatal hernia and intestinal duplication. All 11 cases were confirmed by induction of labor or intrauterine MRI. Conclusions: Fetus with right isomerism syndrome has its characteristic cardiac malformation, and abnormal return of the body and pulmonary veins can help to evaluate its prognosis.
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Received: 25 August 2017
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[1]Yan YL, Kenny BLT, Yeo GSH. Right atrial isomerism-preponderance in Asian fetuses. Using the stomach distance ratio as a possible diagnostic tool for prediction of right atrial isomerism[J]. Ann Acad Med Singapore, 2008, 37(11): 906-912.
[2]Mortari EP, Baban A. Heterotaxy syndrome with and without spleen: different infection risk and management[J]. J Allergy Clin Immunol, 2017, 139(6): 1981-1984.
[3]李雪蕾，韦丹琼，黄婷，等. 产前超声诊断胎儿内脏异位综合征[J]. 中国超声医学杂志，2014，30（8）：727-729.
[4]Hsu JY, Chen SJ, Wang JK, et al. Clinical implication of hiatal hernia in patients with right isomerism[J]. Acta Pediatr, 2005, 94(9): 1248-1252.
[5]Anagnostopoulos PV, Pearl JM, Octave C, et al. Improved current era outcomes in patients with heterotaxy syndromes[J]. Eur J Cardiothorac Surg, 2009, 35(5): 871-877.
[6]Ide Y, Murata M, Ito H, et al. A successful staged fontan operation for a right atrial isomerism neonate having major aortopulmonary collateral arteries and extracardiac total anomalous pulmonary venous connection[J]. Inter Cardio Vasc Thor Surg, 2017, 24(1): 135-137.
[7]Bhaskar J, Galati JC, Brooks P, et al. Survival into adulthood of patients with atrial isomerism undergoing cardiac surgery[J]. J Thorac Cardiovasc Surg, 2015, 149(6): 1509-1513.
[8]Imai K, Murata M, Ide Y, et al. Long-term outcome of patients with right atrial isomerism after common atrioventricular valve plasty[J]. Eur J Cardio-Thorac Surg, 2017, 51(5): 987-994. |
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