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| The diagnostic value of prenatal ultrasound for fetal brain malformations during 11～14 weeks of gestation |
| DENG Feng-lian, GUO Yan-li, DUAN Ling-min, XUE Ya-fang, LIU Jian-jun, WANG Yan, TIAN Tian |
| Department of Ultrasound, Southwest Hospital, Army Medical University, Chongqing 400038, China |
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Abstract Objective: To investigate the prenatal ultrasound of the diagnosis of value of the clinical application of fetal brain malformations at 11～14 weeks of gestation. Methods: Seventy-one cases of brain malformation fetus as the research object from January 2012 to May 2017 in Southwest Hospital, and ultrasonographic characteristics, clinical data and follow-up results of fetuses with brain malformations were retrospectively analyzed. Results: Among 63 cases of brain malformations diagnosed by ultrasound, 17 cases were anencephaly, 21 cases were encephalomegaly, 8 cases were meningocele and 17 cases were whole forebrain. Eight cases of brain malformations were not detected by ultrasonography during 11~14 weeks of pregnancy, including 6 cases of hydrocephalus, 1 cases of complete forebrain deformities, and 1 cases of meningoele. Among 63 cases of 11~14 gestational weeks, 25 cases(39.7%) were complicated with other system or organ abnormalities, of which 17 cases were complicated with multiple malformations. Conclusion: Prenatal ultrasound has a high diagnostic value for fetal brain abnormalities at 11~14 gestational weeks, by providing important evidence for early clinical intervention.
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Received: 23 October 2017
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2018, Vol. 29 
