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Two-dimensional speckle tracking combined with plasma brain natriuretic peptide concentrations#br#
predictive value of left ventricular systolic function in patients with#br#
severe mitral insufficiency during perioperative period |
LI Jie-ming, WU Jun, LIU Ji-hong, YUAN Wei, WEN Xiao-na, CAI Meng, YU Su, YANG Yan, GU Wen-hui |
The Second Affiliated Hospital of Dalian Medical University, Dalian Liaoning 116027, China |
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Abstract Objective: To investigate the predictive value of left ventricular longitudinal strain and plasma brain natriuretic peptide (BNP) concentration on left ventricular systolic function in patients with severe mitral insufficiency during perioperative period. Methods: Thirty mitral insufficiency patients under mitral valve repair or replacement were enrolled for the study. According to postoperative left ventricular ejection fraction(LVEF) greater than or equal 50%(group A) to or less than 50%(group B), they were divided into two groups. Left ventricular global longitudinal strain(GLS) and serum BNP were measured before operation and on the postoperative 7th day. Results were compared and analyzed. Results: There was no significant difference in LVEF between the two groups before operation. The absolute value of GLS on the postoperative 7th day was lower than that in the preoperative level in both two groups. The absolute value of GLS in group B was lower than that in group A, but the plasma BNP concentration in group B was higher than that in group A(P<0.05). The postoperative LVEF was negatively correlated with GLS, positive correlation with postoperative BNP(P<0.05). GLS was the independent predictors of postoperative LVEF reduction. Conclusion: GLS along with BNP were sensitive paramerers of left ventricular systolic function for evaluation the patients with mitral insufficiency during perioperative period.
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Received: 30 September 2017
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