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| Analysis of bone metastasis screening by radiological examination for newly diagnosed patients with
esophageal squamous carcinoma |
| ZHENG Xiao-dong, ZHANG Wei-min, HOU Jian-bin |
| Department of Thoracic Surgery, Anyang Tumor Hospital, Anyang Henan 455000, China |
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Abstract Objective: By analyzing the clinical characteristics of newly diagnosed 376 patients with esophageal squamous carcinoma, to evaluate the incidence of bone metastasis and discuss the necessity of bone scintigraphy for bone metastasis screening. Methods: We retrospectively reviewed the charts of 376 consecutive patients with a pathology diagnosis of esophageal squamous carcinoma in our department between March 2015 and June 2017, and evaluated gender, age, tumor location, TNM staging, and pain. Results: The rate of bone metastasis was 6.4%(24/376), the pain, M1, and agedness were significantly higher(P＜0.05) in positive patients with bone metastasis than negative patients, but no significant difference in gender, tumor location, cT, cN, cTNM staging(P＞0.005). Multivariate binary logistic regression analysis suggested that pain, M1,agedness were independent predictors of bone metastasis. Among 24 patients with bone metastasis, 29.2%(7/24) cases were Tis-2N0M0. Conclusions: For newly diagnosed patients with esophageal squamous carcinoma, bone metastasis may occur in patients with any cT, cN, cTNM and tumor location. Bone scintigraphy was necessary and the first preferred imageological examination for bone metastasis screening, especially for patients with M1, pain and advanced age.
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Received: 11 December 2017
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