18F-FDG PET/CT在成人Still病中的表现及其评估疾病活动度的作用

doi:10.12117/jccmi.2020.05.015

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Abstract Objective: To investigate the expression of 18F-FDG PET/CT in patients with adult-onset Still’s disease (AOSD) and its role in disease activity. Methods: 46 patients who was diagnosed as AOSD were selected and underwent 18F-FDG PET/CT. The clinical manifestations, laboratory examination and characteristics of PET/CT were collected. Then the correlation between SUV intensity of liver, spleen, bone marrow, lymph node and laboratory indexes, system scores were analyzed. Results: 18F-FDG accumulation occurred mainly in bone marrow(100%, SUV intensity: 2.00±0.66), Spleen(96%, SUV intensity:1.70±0.54) and lymph nodes(98%, SUV intensity: 2.67±1.38). In addition, 18F-FDG uptake can also occur in the pericardial pleural, parotid gland, thyroid, skin, joint esophagus and cardia. SUV intensity of bone marrow was significantly correlated with systemic score, ESR, C-reactive protein, WBC and NEU%(r=0.445, 0.376, 0.323, 0.439, 0.524, P<0.05). SUV intensity of spleen was significantly correlated with system score and LDH(r=0.424, 0.347, P<0.05). SUV intensity of lymph node was significantly correlated with disease system score(r=0.356, P<0.05). Conclusion: 18F-FDG accumulation occurred mainly in bone marrow, spleen and lymph nodes. 18F-FDG PET/CT is helpful for the differential diagnosis and monitoring of disease activity.

Key words： Still's disease, adult-onset Positron-emission tomography Tomography, spiral computed

Received: 08 August 2019

PACS:	Ｒ593
	Ｒ817.4

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	LI Shi-yang
	ZHANG Xiao-li

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LI Shi-yang,ZHANG Xiao-li. Imaging of 18F-FDG PET/CT in adult-onset Still’s disease and its role in the assessment of disease activity[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(5): 368-371.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2020.05.015 OR http://www.jccmi.com.cn/EN/Y2020/V31/I5/368

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