Abstract Objective: To investigate the effects of hypercholesterolemia on cardiovascular disease and the application of ultrasound in patients’ cardiac examination. Methods: Sixty patients diagnosed with hypercholesterolemia who were admitted to our department of cardiology from July 2018 to July 2019 were selected as subjects. Sixty patients with normal serum cholesterol levels were selected as the control group. Ultrasound was used to determine whether there was stenosis and reflux in the heart valves of the two groups of patients. Left ventricular peak filling rate(LVPER) and left ventricular ejection fraction(LVEF) were measured in the two groups. The aortic root diameter and the ascending aorta diameter were examined in both groups. Results: The proportion of aortic regurgitation(26.7% vs. 8.3%) and stenosis(15.0% vs. 3.3%) and mitral regurgitation(18.3% vs. 5.0%) and stenosis(11.7% vs. 1.7%) were significantly higher in the hypercholesterolemia group than in the control group(P<0.05). LVPER((1.71±0.25) vs. (1.82±0.27)) and LVEF((53.36±4.18)% vs. (55.47±4.72)%) were significantly lower in the hypercholesterolemia group than in the control group(P<0.05). The diameter of the aortic root ((35.37±3.92) mm vs. (32.17±3.64) mm) and the diameter of the ascending aorta((34.91±3.71) mm vs. (31.64±4.52) mm) were significantly higher in the hypercholesterolemia group than in the control group(P<0.05). Conclusion: Hypercholesterolemia can affect heart valve and aortic function, and ultrasonography can effectively check for heart valve and aortic function-related diseases.
MI Jia,YAN Juan,WANG Jia-qiang. Effect of hypercholesterolemia on cardiac ultrasound indicators[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(6): 422-424.
