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The correlation between high resolution CT findings and recovery of respiratory function tests in SARS patients in the convalescent phase |
LAN Ri-hui1, ZENG Qing-si1, SUN Chong-peng1, CHEN Ling1, ZHENG Ze-guang2, ZHENG Jin-ping2, WU Hua2 |
1.Department of Radiology, First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510120, China;2.Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China |
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Abstract Objective: To study the correlation between high resolution CT(HRCT) findings, recovery of respiratory function tests and clinical data of SARS patients in the convalescent phase. Methods: Forty-nine patients with confirmed SARS underwent initial thin-section CT and forty patients underwent respiratory function tests. Sixteen and thirteen patients underwent follow-up examination. The clinical data were retrospectively analysed. CT visual score were quantitatively analyzed for lung abnormalities. Results: Ground-glass opacities and interstitial opacities were found in 25(51%), 22(45%) of the 49 patients on initial HRCT and in 6(38%), 7(44%) of the 16 patients on the follow-up HRCT examinations. The initial and follow-up CT visual score indicated a significant reduction in the extent of ground-glass opacity(P<0.001) but not in that of interstitial opacity. Scan from patients with adult respiratory distress syndrome(ARDS) had a significantly higher score for ground-glass opacity than did those from patients without ARDS(P<0.05). Dlco% were correlated with sex and ground-glass opacity score. Conclusion: HRCT findings were correlated with clinical data, laboratory tests and respiratory function tests, residual abnormalities and respiratory function tend to be better over the time, but interstitial opacity persists.
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Received: 27 December 2005
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