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| Study the hemodynamics of central retinal artery and posterior ciliary arteryin diabetic retinopathy with color Doppler ultrasonography |
| NIE Fang, TONG Ming-hui, CHE Yan |
| Department of Ultrasound, the Second Hospital of Lanzhou University, Lanzhou 730030, China |
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Abstract Objective: To study the hemodynamics of posterior ciliary artery(PCA) and central retinal artery(CRA) in diabetic retinopathy(DR) with color Doppler ultrasonography and the correlation between glycohemoglobin(GHb) and hemodynamics. Methods: We measured the peak systolic velocities(PSV), the end diastolic velocities(EDV), the resistive index(RI) of CRA and PCA with color Doppler ultrasonography and GHb in 67 patients with diabetes and 40 normal volunteers, the correlation between GHb and hemodynamics were analysed. Result: Reduced blood flow velocity and increased resistance of CRA and PCA was found in patients with diabetes and appeared to become further reduce in PSV, EDV and increase in RI with the progression of retinopathy. The alteration of CRA has statistically significance compared to PCA. The hemodynamic alteration of CRA and PCA appeared before retinopathy. The GHb has positive correlation with blood flow velocity and correlation with RI. Conclusion: Reduced blood flow velocity and increased resistance were the characteristics of ophthalmic hemodynamics in diabetic retinopathy. The alteration of CRA hemodynamics correlated with GHb significantly.
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Received: 24 August 2005
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2006, Vol. 17 
