|
|
|
| Evaluation of interictal PET and ictal SPECT brain imagingin localizing the foci of intractable epilepsy in children |
| SUN Ai-jun, SU Wen-cong, LI Shu-sheng, LIU Jian, SU Fu-yong, WEI Qiang, DU Jing-bo, LIU Jie |
| PET Center, Shandong Zibo Wanjie Hospital, Zibo Shandong 255213, China |
|
|
|
|
Abstract Objective: To evaluate the value of interictal PET and ictal SPECT brain imaging in localizing the foci of intractable epilepsy in children. Methods: Thirty pediatric patients with intractable epilepsy were performed with interictal PET and ictal SPECT brain imaging. The results were compared and analysed. Results: In interictal PET, 16 patients showed local single lobe hypo-metabolism, multi-lobe and diffuse hypo-metalism in 14 patients. During ictal SPECT studies, 18 showed hyper-perfusion in solitary lobe, multi-hyper-perfusion foci in 10 patients. Compared the two examinations, 26(86.7%) were accorded with each other in 30 patients. Of the 12 patients with multiple and diffuse hypometabolism in interictal PET, 6 patients showed foci changed to solitary focal hyper-perfusion in ictal SPECT. Conclusion: Interictal PET combined with ictal SPECT can learn from others’s strong points to offset one’s weakness, elevate the accuracy in localizing epileptic foci, offer more reliable messages for treatment.
|
|
Received: 24 August 2005
|
|
|
|
|
|
|
|
|
2006, Vol. 17 
