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| Evaluating left ventricular function in congestive heart failure before and after treatment assessed by Doppler tissue imaging |
| XU Dong-mei1, FAN Chong-lun2, ZHANG Mei1, ZHANG Yun1 |
| 1. Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China; 2. Department of Respiratory Medicine, the Center Hospital of Jinan, Jinan 250013, China |
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Abstract Objective: To analyse the correlation of parameters between left ventricular systolic function, functional class, and the systolic and diastolic function of left ventricle before and after treatment by Doppler tissue imaging(DTI). Methods: Thirty-four consecutive patients with a clinical diagnosis of congestive heart failure were studied by DTI. Four sites at mitral annuli were selected corresponding to the septal, lateral, anterior and inferior walls of the ventrical from apical 4- and 2-chamber views. We detected wall motion of mitral valve annulus and recorded DTI indexes included the peak systolic velocities(Sa), the peak early and late diastolic velocities(Ea and Aa). Sa/Ea and VMS were calculated. Thirty-four normal subjects were selected as control group. Results: Sa derived from the lateral site of mitral annulus from apical four-chamber view correlated well with functional class(rs=-0.65, P<0.0001), the 4-site average velocities of mitral annulus correlated better with functional class(rs=-0.69, P<0.0001). Compared with healthy controls, Sa and Ea of all 4 sites were significantly decreased(P<0.001), Ea/Sa significantly increased(P<0.01). After treatment, Sa and Ea of all 4 sites were significantly increased(P<0.001), Ea/Sa significantly decreased(P<0.01). Conclusions: Left ventricular systolic and diastolic function could be quantitatively analyzed by DTI, there are more close correlation between the 4-site average velocities of mitral annulus VMS and NYHA functional class.
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Received: 22 December 2005
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2006, Vol. 17 
