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| Comparison of the differential diagnostic value of CT perfusion, MR perfusion and DWI in liver diseases |
| SHI Li-jing1, LI Shu-ping2, TIAN Jian-ming3, CHEN Wei3, WANG Jian3 |
| 1. MRI Room, Imaging Center, Navy General Hospital, Beijing 100037, China; 2. CT Room, 455th Hospital of PLA, Shanghai 200052, China; 3. Department of Radiology, Changhai Hospital, the Second Medical University of PLA, Shanghai 200433, China |
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Abstract Objective: To compare the differential diagnostic value of CT perfusion, MR perfusion and DWI in benign lesion, malignant lesion, cirrhosis and normal liver. Methods: Fifty cases underwent DWI, CT perfusion and MR perfusion, including 11 normal volunteers, 16 cirrhosis, 13 malignant liver lesions and 10 benign lesions. ADC value of each case was calculated and the results between the 4 groups were compared. When CT and MR perfusion was finished, separate the perfusion curve of liver lesion and hepatic parenchyma into two parts according to the TTP of spleen, calculate the SS of each part, then get the ratio of the two SS, named SSr(ct)=SSpre/SSpost to CT perfusion and SSr(mr)=SSpre/SSpost to MR perfusion. Then compare SSr(ct) and SSr(mr) between the 4 groups. Results: The ADC value of malignant lesion, benign lesion, cirrhosis and normal liver was(1.02±0.15)×10-3mm2/s, (2.21±0.74)×10-3mm2/s, (1.33±0.12)×10-3mm2/s and (1.50±0.11)×10-3mm2/s, respectively. The difference between each 2 groups were significant(P<0.05), except the result between cirrhosis and normal liver(P>0.05). The SSr(ct) and SSr(mr) of malignant tumors were 1.52±0.60 and 1.79±0.35, the results of benign lesions were 1.26±0.41 and 1.19±0.36, results of normal liver were 0.72±0.26 and 0.66±0.24, as to cirrhosis, the results were 1.38±0.39 and 1.83±0.59. The difference between each 2 groups were not significant(P>0.05), except the result between cirrhosis and normal liver, and the result between malignant tumors and normal liver(P<0.05). Conclusion: To different benign from malignant lesion, cirrhosis from those benign or malignant lesions, DWI may have more advantage than CT and MR perfusion, while CT and MR perfusion have more advantage in the diagnosis of cirrhosis.
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Received: 23 July 2007
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2007, Vol. 18 
