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| The ROC curve analysis of color Doppler ultrasound in differentiation of benign and malignant solid superficial soft tissue tumors |
| XU Dong-yang, WANG Xue-mei |
| Department of Ultrasound, the First Affiliated Hospital of China Medical University, Shenyang 110001, China |
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Abstract Objective: To investigate the value of color Doppler ultrasound in differentiation of benign and malignant solid superficial soft-tissue tumors using receiver operation characteristic curve(ROC curve). Method: Ninty-two solid superficial soft-tissue tumors were studied using combination of two-dimensional and color Doppler ultrasound and compared with the pathologic results. The tumors were evaluated semi-quantitatively to get the ROC curve and the Youden index according to the tumors’ size, margin, configuration, homogeneity and blood flow. Results: The color ultrasound demonstrated all the 92 tumors including 72 benign and 20 malignant ones. The area under the ROC curve was 0.994(P<0.001), and the Youden index was 10. Conclusion: The color ultrasound is accurate in the differentiation of benign and malignant superficial soft tissue tumors, and plays a directive role in treatment planning.
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Received: 22 January 2007
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Corresponding Authors:
WANG Xue-mei
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2007, Vol. 18 
