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Assessment of left ventricular function by strain rate imaging in patients with anomalous origin of the left coronary artery from the pulmonary artery |
WU Li-jun1, ZHANG Yu-qi2, SUN Kun2, YI Xiao-lei2, NI Jin-hong1, GAO Ling-ling1, YU Yi1, WANG Jie1 |
1. Department of Echocardiography, Xinhua Hospital, Shanghai Jiaotong University, Shanghai 200092, China; 2. Department of Pediatric Cardiology, Shanghai Children’s Medical Center, Shanghai Jiaotong University, Shanghai 200127, China |
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Abstract Objective: To explore the accuracy of strain rate imaging(SRI) in quantitative assessment of left ventricular function in patients with anomalous origin of the left coronary artery from the pulmonary artery(ALCAPA). Methods: Thirty-nine healthy subjects and 16 children with ALCAPA were studied. Regional strain rate in the mid, basal and apical segment of left ventricular wall and septum in systolic, early diastolic and late diastolic period and the systolic strain were measured, and these data were compared and analyzed. Results: The parameters of systolic strain and strain rate, diastolic strain and strain rate in the ALCAPA group before operation are significantly lower than that in the normal group(P<0.01). After coronary reimplantation, these parameters increased more significantly(P<0.01), but still lower than that in the normal group(P<0.05). Conclusions: Compared with normal children, left ventricular function is impaired in patients with ALCAPA, coronary reimplantation should be performed early to improve ventricular function. The change of left ventricular function before and after operation in patients with ALCAPA could be accurately assessed by strain rate imaging.
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Received: 22 February 2008
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Corresponding Authors:
ZHANG Tu-qi
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