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| Study of signal variation on diffusion-weighted MRI of cerebral cortices in healthy adults |
| ZHU Jian-zhong1, ZHAO Lei1, QIN Jian2, CHENG Yu-hui1, LIU Jun-jie2 |
| 1. Imaging Center, Affiliated Hospital of Taishan Medical College, Taian Shandong 271000, China;2. Taishan Medical College, Taian Shandong 271000, China |
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Abstract Objective: To determine whether there is regional signal variation in the brain cortices of neurologically healthy adults on DW-MR images. Materials and Methods: The signal intensity(SI) on DW-MR images, contrast-to-noise ratios(CNR), and apparent diffusion coefficient(ADC) maps of the cerebral cortices at Signa HDe 1.5T were evaluated in 47 neurologically healthy subjects(27 men, 20 women, age range 31~82 years). Results: Increased SI on DW-MR images was seen in the cingulate gyrus and insula regardless of patient age. There were no statistically significant gender-or laterality-related differences(P>0.05). There was statistically significant differences existed in CNR among the cortical regions(P<0.001), and the signal intensity was higher in the cingulate gyrus and insula than in the other cortices(P<0.01). There were no apparent ADC differences among the cortices on ADC maps in males and females(P>0.05). Conclusion: The signal of brain cortices in the cingulate gyrus and insula was observed on DW-MR images of healthy subjects, and frequently manifest high SI. These findings may help in the recognition of cortical signal abnormalities as visualized on DW-MR images.
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Received: 04 August 2009
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2010, Vol. 21 
