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Comparison of 11C-MET PET/CT and MRI for the diagnosis of gliomas before operation |
WANG Ru, QIAN Li-ting, WANG Shi-cun, ZHAN Feng-lin, PAN Bo, ZHANG Hong-yan, MA Jun |
Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China |
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Abstract Objective: To evaluate the value of 11C-MET PET/CT and MRI for the diagnosis of gliomas before operation. Methods: We examined 11 patients prospectively with newly diagnosed gliomas based on brain MRI before operations. 11C-MET PET/CT was performed on these patients and then compared with their histological analysis. Results: Of all the eleven patients, ten were confirmed to be gliomas, except one glial cell hyperplasia. The sensitivity, specificity and accuracy of 11C-MET PET/CT and MRI for diagnosis of gliomas before operation were 100%, 100%, 100% and 100%, 0, 91%, respectively. Conclusion: 11C-MET PET/CT is more helpful than MRI for diagnosis of gliomas before operation.
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Received: 23 December 2011
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Corresponding Authors:
QIAN Li-ting
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