|
|
|
| Meta-analysis of low-dose CT for urolithiasis |
| PU Zu-hui, YIN Jun-ming, LIU Wei-zong |
| The First Hospital of Shenzhen University, Shenzhen Guangdong 518035, China |
|
|
|
|
Abstract Objective: To summarize the accuracy of low-dose CT(LDCT) for urolithiasis with Meta-analysis. Materials and Methods: Published studies were identified by Pub/Medline and Ovid databases and Chinese databases(1990—2011) in search of LDCT studies for urolithiasis. A standard extractive database was obtained. Inclusion and exclusion criteria were used to extract relevant data. QUADAS was analyzed. Using software Excel 2003 and Metadisc 1.4, the summary sensitivity and specificity, summary positive likelihood ratio and summary negative likelihood ratio were caculated. Heterogeneity and biase were also evaluated. Result: Of 264 identified studies, 9 involving studies were considered appropriate for pooled analysis. There were 1298 cases all together. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio were 0.959(95% CI: 0.944～0.972), 0.957(95％ CI: 0.934～0.973), 17.853(95％ CI: 11.735～27.161) and 0.045(95％ CI: 0.025～0.078), respectively. Conclusion: LDCT is of high specificity and sensitivity for urolithiasis. But there were biases in the studies and appropriate studies are needed.
|
|
Received: 17 November 2011
|
|
|
|
|
|
|
|
|
2012, Vol. 23 
