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| Comparative studies of the value of 18F-FDG PET and EEG in temporal epilepsy patients |
| ZHAO Chun-lei1, CHEN Zi-qian1, LIU Yao2, QIAN Gen-nian1，YANG Zhong-dong1, WANG Kai-tang1, LI Ming-shan1 |
| 1.Department of Medical Imaging of Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China;2.Department of Medical Imaging, the Second Affiliated Hospital, Fujian University of Traditional Chinese Medicine,Fuzhou 350003, China |
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Abstract Objective: To prospectively evaluate the efficacy of 18F-FDG PET/CT brain imaging and electroencephalogram(EEG) in preoperative localization of temporal lobe epileptic focus in 62 patients. Methods: Sixty-two patients who were clinically diagnosed as temporal lobe epilepsy and received surgical treatment were prospectively studied. All of those patients underwent interictal PET-CT brain imaging examination and long-range/video EEG examination prior to surgery. The researchers analyzed all the images and test results obtained and compared with postoperative pathology. The diagnostic accuracy between the two methods were compared and analyzed using statistical methods. Results: The rate of accuracy in locating epileptic focus was 67.7%(42/62) for PET/CT brain imaging and 48.4%(30/62) for long-range or video EEG, there was significant difference of accurate localization rate between the two methods(P<0.05). Conclusion: Interictal PET-CT brain imaging is better than long-distance/video EEG examination in preoperative localization of temporal lobe epileptic focus. PET-CT brain imaging is too expensive, so EEG can be used as the preferred method in the clinical application. PET imaging can significantly improve the rate of accuracy in locating epileptic focus when there are difficulties in the localization of temporal lobe epileptic focus with EEG.
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Received: 08 December 2011
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2012, Vol. 23 
