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Correlation between intima-media thickness of the carotid artery and left ventricular remodeling inessential hypertension patients |
ZHANG Xiao-hong1, CHE Zheng-lan2 |
1.Department of Ultrasound, Affiliated Huaihe Hospital of Henan University, Kaifeng Henan 475000, China;2.Department of Ultrasound, Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China |
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Abstract Objective: To investigate the relationship between carotid artery intima-media thickness(IMT) and left ventricular remodeling in essential hypertension(EH) patients. Methods: Carotid and cardiac ultrasonography were performed on 78 patients with EH from our hospital and 30 healthy aged persons were selected as normal control. The interventricular septum thickness(IVST), left ventricular posterior wall thickness(LVPWT), left ventricular end diastolic diameter(LVDd), intima-media thickness in common carotid artery(CCA-IMT) and its bifurcation(BIMT), plaque and hemodynamic parameters in carotid artery were measured respectively, according to corresponding formula to obtain left ventricular mass index(LVMI). According to left ventricular mass index(LVMI), EH patients were divided into left ventricular hypertrophy(LVH) group and non-left ventricular hypertrophy(NLVH) group. Statistical analysis was carried out. Results: The IMT and BIMT were higher in EH group than those in the control group, and LVH group is the highest among the three groups. The prevalence of carotid plaque in EH group was higher than that in control group. Compared with the control group, peak systolic velocity(PSV) of carotid artery was lower in EH group, whereas resistance index(RI) and pulsatility index(PI) were higher. There were positive correlation between LVMI and CCA-IMT, BIMT, RI, PI, and negative correlation between LVMI and PSV. Conclusion: Color Doppler ultrasound is a reliable method to detect the carotid remodeling and left ventricular remodeling in EH patients. The occurrence of carotid remodeling is earlier than that of the left ventricular myocardial remodeling, and there is a close correlation between them.
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Received: 05 January 2012
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