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Role of color Doppler ultrasound in evaluation of breast cancer during neoadjuvant chemotherapy |
HU Zheng-ming, SUN De-sheng, ZHONG Jie-yu, WEI Wei, HAN Bin, HU Hui-ying, GONG Ji-jun |
Peking University Shenzhen Hospital, Shenzhen Guangdong 518036, China |
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Abstract To assess the value of color Doppler ultrasound(CDU) in evaluating the response of breast cancer to neoadjuvant chemotherapy(NAC). Materials and Methods: This study included 53 patients with 57 breast cancer who were treated with NAC between January 2009 and June 2012. All patients were evaluated by CDU before and after NAC. The tumor sizes, peak systolic velocity(PSV), distribution of blood flow and RI index were observed. All patients were divided into effective group(CR+PR group) and ineffective group(SD+PD group). Results: Five patients were CR; In PR group, after NAC, resistive index(RI) and distribution of blood flow decreased(P<0.01), but PSV did not change; In the ineffective group, PSV, RI and distribution of blood flow did not change(P>0.05). Conclusion: CDU is an effective method for evaluating the response of breast cancer to NAC.
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Received: 02 April 2013
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