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| Relevance analysis among X-ray image and bone density, ash weight, calcium and phosphorus element in the healing process of experimental tibial fracture |
| ZHAO Shu-ying, ZHANG Wan-qiang, GENG Jin-chao, ZHANG Jing-guo |
| Wangjing Hospital of CACM, Beijing 100102, China |
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Abstract Objective: To observe in experimental tibial fracture healing process, the X-ray appearance and bone density, ash weight, calcium and phosphorus element content changes, so as to determine the X-ray features at different periods of fracture healing and to guide clinical rehabilitation treatment. Methods: Sixty rats of (250±10) g were randomly divided into 2 groups. Sawing accident was used to cause defect in the tibial fracture model in the experimental group. Control group received no treatment. Sampling was taken 2 weeks and 4 weeks after surgery to get X-ray films and bone density, ash weight, calcium and phosphorus element. Content of calcium and phosphorus was taken 2 weeks after operation. Results: After 2 weeks, bone density and ash weight, calcium and phosphorus element content showed significant difference betwee two groups. On X-ray films, the experimental group showed fuzzy fracture line, higher density lesions in the end and a small amount of callus formation. The pathology proved new bone trabecular formation. After 4 weeks, bone density and ash weight showed no significant differences between two groups. In the experimental group, callus was obvious on X-ray film. The pathology proved the trabecular bone became bulky and gradually merged into trabular bone. Conclusion: During fracture healing process, X-ray features are positively correlated with bone density, ash weight, calcium and phosphorus element content and pathological changes, which can determine fracture healing and guide clinical rehabilitation.
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Received: 27 March 2015
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Corresponding Authors:
GENG Jin-chao
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2015, Vol. 26 
