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| Evaluation of solitary pulmonary nodule on iodine mapping of dual-energy CT |
| Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China |
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Abstract Objective: To evaluate the value of iodine mapping of dual-energy CT(DECT) in differential diagnosis of solitary pulmonary nodule(SPN). Methods: Sixty-eight patients with SPNs proved by pathology underwent DECT scans. The iodine images were derived from the arterial phase(AP) and venous phase(VP) using software of dual-energy processing. CT numbers of SPN on enhanced weighted images and iodine-enhanced images and iodine value were measured, and their diagnostic value was evaluated basing on pathological results. Results: In 68 proved cases of SPN, 48 cases were malignant, including adenocarcinoma(n=36), squamous carcinoma(n=5) and small cell carcinoma(n=7), and 20 cases were benign, including inflammation(n=7), tuberculosis(n=10), adenoma(n=2) and hamartoma(n=1). There were significantly higher degree of enhancement(△CT), CT number on the iodine-enhanced images(Overlay) and the standardization of iodine value(NIV) in malignant group than benign group in both AP and VP(P<0.05). The △CT value was less than the overlay in both AP and VP and was statistically significant difference in malignant group in VP(P<0.05). Conclusion: The iodine mapping of DECT is helpful for differential diagnosis of SPN.
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Received: 18 May 2015
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