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| A study on the relationship between epicardial adipose tissue density and coronary artery plaque |
| LI Jian, GUO Qing-le, ZHAO Jing, LIU Jing-wang, ZHOU Rui-chen, GAO Yu-long, CUI Liu-fu, QIAO Jian-min |
| Department of Imaging, the Kailuan Affiliated Hospital, Hebei United University, Tangshan Hebei 063000, China |
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Abstract Objective: To explore the relationship between epicardial adipose tissue(EAT) and coronary artery plaque. Methods: 417 patients suspected with coronary artery disease underwent coronary artery CT angiography. EAT density of each subject was semiautomatically calculated. The patients were divided into plaque and no plaque group based on coronary artery CT angiography, and the plaque group were subdivided into calcified, mixed and non-calcified plaque group. EAT density in each group was compared according to gender and age． Results: 417 patients were enrolled in this study. Among 184 patients with coronary artery plaque, 42 were calcified, 59 were non-calcified, 83 were mixed and 228 had no plaque. EAT density was significantly increased in the coronary artery plaque patients． Significant difference in EATV was observed between the plaque and no plaque groups(40.84±37.28 vs. 23.81±30.81, P=0.000) with no relationship to gender(male, t=8.78, P=0.000, female, t=5.941, P=0.000). There was significant difference between the plaque and non-plaque groups in EAT density by different age groups(＜45 years t=7.012, P=0.000, 45~＜55 years t=3.459, P=0.002, 55~＜65 years t=5.416, P=0.000, ≥65 years t=7.750, P=0.000). There was significant difference between different plaque characteristics in EAT density(calcified plaque groups t=4.426, P=0.000, non-calcified plaque groups t=6.784, P=0.000, mixed plaque groups t=6.710, P=0.000). Conclusions: EAT density was correlated with coronary artery plaque with a close relationship to plaque characteristic.
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Received: 30 July 2014
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2015, Vol. 26 
