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IOTA simple rules in differentiating between benign and malignant ovarian tumors |
MENG Lu, WANG Xin-lu, SHI Tie-mei |
Department of Ultrasound, Shengjing Hospital, China Medical University, Shenyang 110004, China |
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Abstract Objective: To evaluate the diagnostic value for identifying benign and malignant ovarian tumors by the international ovarian tumor analysis(IOTA) simple rules. Materials and Methods: The patients with ovarian masses accepted surgery between January 2013 and November 2014 were calculated. All patients underwent ultrasound examination for IOTA simple rules within one week before surgery. All examinations were performed by the first author to identify benign and malignant ovarian masses using IOTA simple rules. Gold standard diagnosis was pathological results. Results: A total of 252 ovarian masses were available for analysis. Two hundred and two cases were applicable for the IOTA simple rules(80.2%), including 151 benign tumors(74.8%) and 51 malignant tumors(25.2%). The simple rules yielded inconclusive results in 50 masses(19.8%). In the 202 masses for which the IOTA simple rules could be applied, sensitivity was 81.8%(95%CI: 71.6%~92.0%) and specificity was 95.9%(95%CI: 92.6%~99.2%). Conclusion: The IOTA simple rules have high diagnostic performance for identifying benign and malignant ovarian tumors. Nevertheless, this situation is not suitable to all tumors.
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Received: 03 January 2015
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Corresponding Authors:
SHI Tie-mei
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