CT平扫对甲状腺单纯粗钙化结节良、恶性的预测价值

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Abstract Objective: To investigate the predictive value of plain CT scan in simple coarse calcific thyroid nodules(SCCN). Methods: The CT data of 92 SCCN in 92 cases confirmed by operation and pathology were retrospectively analyzed, including 57 benign nodules and 35 malignant nodules. The bone window(W 1 000~2 000 HU, L 300~350 HU) and soft tissue window(W 300~350 HU, L 35~40 HU) were used to identify whether SCCN had septa and peripheral artifacts, respectively. The number of benign and malignant nodules which had septa and artifacts were counted, followed by χ2 test for statistical analysis. Results: In 92 SCCN, the proportions of septa, no artifacts and their combination in the benign and malignant nodules were 50.9%(29/57) and 80.0%(28/35)(χ2=7.803, P=0.005), 26.3%(15/57) and 71.4%(25/35)(χ2=17.958, P=0.000), 3.5%(2/57) and 57.1%(20/35)(χ2=34.284, P=0.000), respectively. Their sensitivity and specificity of diagnosing malignant nodules were 80.0%(28/35) and 49.1%(28/57), 71.4%(25/35) and 73.7%(42/57), 57.1%(20/35) and 96.5%(55/57), respectively. The combination of no septa and artifacts in benign and malignant nodules accounted for 38.6%(22/57) and 5.7%(2/35)(χ2=12.162, P=0.000), respectively. Their sensitivity and specificity of diagnosing benign nodules were 38.6%(22/57) and 94.3%(33/35). Conclusion: CT scan for predicting benign and malignant SCCN was of significant value. Septa and no artifacts contributed to the diagnosis of malignant nodules, while no septa and artifacts suggested the diagnosis of benign nodules. Their combination could significantly improve the diagnostic specificity.

Key words： Goiter, nodular Thyroid neoplasms Tomography, spiral computed

Received: 01 April 2016

PACS:	Ｒ581
	Ｒ736.1
	R814.42

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	Articles by authors
	HU Bin1
	LAI Xu-feng2
	HAN Zhi-jiang2
	LEI Zhi-kai2

Cite this article:

HU Bin1,LAI Xu-feng2,HAN Zhi-jiang2, et al. Predictive value of plain CT scan in thyroid benign and malignant simple coarse calcific thyroid nodules[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(11): 774-777.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I11/774

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