实时三维超声心动图区分左心衰合并肺高压不同亚型的研究

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Abstract Objective: Using single cardiac cycle real-time three dimensional echocardiography(sRT-3DE) combined with conventional two-dimensional(2DE) and Doppler echocardiography to differentiate the subtypes of pulmonary hypertension in left ventricular failure(LVF) with reduced ejective fraction(EF). Methods: In the case group, 60 patients with LVEF＜50% measured by sRT-3DE were divided into three subgroups by sPAP and PVR: 15 patients in LVF-NPH group, 15 patients in LVF-PPH group and 30 patients in LVF-RPH group; 35 healthy people were selected as control group. The 2DE and sRT-3DE were performed in all groups to analyze the 2DE, 3DE and Doppler parameters, and the correlation analysis were performed. Results: ①Compared with the control group, the right ventricular EDVI, ESVI increased and LVEF, RVEF decreased in LVF-NPH group; Compared with LVF-NPH group, right ventricular ESVI increased and LVEF decreased in LVF-PPH group; Compared with the LVF-PPH group, the right ventricular EDVI, ESVI increased and LVEF, RVEF decreased in LVF-RPH group(P＜0.05）. ②There was significant correlation between PVR and sPAP. The correlations of PVR with RVEF, RVFAC and TAPSE were better than those of sPAP, but the correlations of PVR with RVEDV and RVESV were worse than those of sPAP. ③The AUCs of ROC curve of RVEDVI, RVESVI and RVEF to differentiate RPH were 0.732, 0.844 and 0.904, respectively, which indicated excellent sensitivity and specificity. Conclusion: sRT-3DE combined with the traditional 2DE and Doppler echocardiography can accurately assess the state of the right ventricular structure and function and differentiate the subtypes of PH in patients with LVF.

Key words： Heart failure, congestive Hypertension, pulmonary Echocardiography, Doppler, color

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	BAI Yang
	YANG Jun
	WANG Xu
	YAN Hong

Cite this article:

BAI Yang,YANG Jun,WANG Xu, et al. Real-time three dimensional echocardiography differentiating#br# the subtypes of pulmonary hypertension in left heart failure[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(6): 393-396.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I6/393

[1]Galie N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension[J]. Eur Respir J, 2009, 34(6): 1219-1263.
[2]Rudski LG, Lai WW, Afilalo J, et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography[J]. J Am Soc Echocardiogr, 2010, 23(7): 685-713.
[3]Abbas AE, Fortuin FD, Schiller NB, et al. A simple method for noninvasive estimation of pulmonary vascular resistance[J]. J Am Coll Cardiol, 2003, 41(6): 1021-1027.
[4]Aronson D, Eitan A, Dragu R, et al. Relationship between reactive pulmonary hypertension and mortality in patients with acute decompensated heart failure[J]. Circ Heart Fail, 2011, 4(5): 644-650.
[5]Khush KK, Tasissa G, Butler J, et al. Effect of pulmonary hypertension on clinical outcomes in advanced heart failure: analysis of the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness(ESCAPE) database[J]. Am Heart J, 2009, 157(6): 1026-1034.
[6]Kjaergaard J, Akkan D, Iversen KK, et al. Prognostic importance of pulmonary hypertension in patients with heart failure[J]. Am J Cardiol, 2007, 99(8): 1146-1150.
[7]Georgiopoulou VV, Kalogeropoulos AP, Borlaug BA. et al. Left Ventricular Dysfunction With Pulmonary Hypertension Part 1: Epidemiology, Pathophysiology, and Definitions[J]. Circ Heart Fail, 2013, 6(2): 344-354.
[8]Selimovic N, Rundqvist B, Bergh CH, et al. Assessment of pulmonary vascular resistance by Doppler echocardiography in patients with pulmonary arterial hypertension[J]. J Heart Lung Transplant, 2007, 26(9): 927-934.
[9]Rajagopalan N, Simon MA, Suffoletto MS, et al. Noninvasive estimation of pulmonary vascular resistance in pulmonary hypertension[J]. Echocardiography, 2009, 26(5): 489-494.
[10]Opotowsky AR, Clair M, Afilalo J, et al. A simple echocardiographic method to estimate pulmonary vascular resistance[J]. Am J Cardiol, 2013, 112(6): 873-882.
[11]白洋，杨军，王玥. 单心动周期实时三维超声心动图对肺高压患者右心功能的研究[J]. 中国医科大学学报，2012，41（3）：244-246.
[12]Kim J, Cohen SB, Atalay MK, et al. Quantitative Assessment of Right Ventricular Volumes and Ejection Fraction in Patients with Left Ventricular Systolic Dysfunction by Real Time Three-Dimensional Echocardiography versus Cardiac Magnetic Resonance Imaging[J]. Echocardiography, 2015, 32(5): 805-812.
[13]Vonk Noordegraaf A, Galie N. The role of the right ventricle in pulmonary arterial hypertension[J]. Eur Respir Rev, 2011, 20(122): 243-253.