胚胎型大脑后动脉伴发颅内动脉瘤的多层螺旋CT血管造影分析

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Abstract Objective: To observe fetal origin of posterior cerebral artery(FTP) accompanied with intracranial aneurysm by CT angiography(CTA). To investigate whether FTP is the risk factor of intracranial aneurysm. To analyze clinical datas(including age, gender, smoking history, hypertension, coronary heart disease and diabetes) of FTP patients whether accompanied with intracranial aneurysm. Methods: Three doctors reviewed intracranial CTA of 155 consecutive patients. Whether the FTP existed or not was observed firstly. Then, FTP type and intracranial aneurysms accompanied with FTP were observed carefully, including aneurysms’ location, size, and subarachnoid hemorrhage. The clinical data including smoking history, hypertension, coronary heart disease and diabetes of patients with FTP were interviewed by telephone. The incidence of FTP, intracranial aneurysms accompanied with FTP and non-FTP were calculated respectively. Gender difference about FTP was analyzed by χ2 test. The incidence of intracranial aneurysms(including accompanied with FTP and non-FTP) and their clinical data were analyzed by Fisher’s exact test. Binary logistic regression analysis was used to evaluate weather FTP is the risk factor of intracranial aneurysm. Results: The FTP incidence was 16.13%(25/155) in overall, 12.12%(12/99) in male, 23.21%(13/56) in female. There was no gender difference in FTP incidence(P=0.071). The incidence of intracranial aneurysms accompanied with FTP and non-FTP was 20%(5/25), 6.15%(8/135), respectively. There was statistical difference in the incidence of intracranial aneurysms between FTP and non-FTP(P=0.038). FTP is the risk factor of intracranial aneurysm(P=0.031). There were statistical differences between intracranial aneurysms accompanied with FTP and non-FTP on gender, hypertension, coronary heart disease and diabetes(P<0.05). On the contrary, there were no statistical difference between above on age and smoking(P>0.05). Conclusions: The incidence of intracranial aneurysms about female patients with FTP is significantly higher when they suffered hypertension, coronary heart disease or diabetes.

Key words： Intracranial aneurysm Posterior cerebral artery Tomography, spiral computed Angiography

Received: 26 November 2015

PACS:	Ｒ739.41
	Ｒ814.42
	Ｒ814.43

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	Articles by authors
	HE Zhen
	ZHANG Ji-yang
	XU Meng
	WAN Ye-da

Cite this article:

HE Zhen,ZHANG Ji-yang,XU Meng, et al. Evaluate fetal origin of posterior cerebral artery accompanied with intracranial aneurysm by CT angiography[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(8): 538-542.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I8/538

[1]Fawcett E, Blachford JV. The Circle of Willis: an Examination of 700 Specimens[J]. J Anat Physiol, 1905, 40(Pt 1): 63-70.
[2]Zada G, Breault J, Liu CY, et al. Internal carotid artery aneurysms occurring at the origin of fetal variant posterior cerebral arteries: surgical and endovascular experience[J]. Neurosurgery, 2008, 63(1 Suppl 1): ONS55-61.
[3]Dimmick SJ, Faulder KC. Normal variants of the cerebral circulation at multidetector CT angiography[J]. Radiographics, 2009, 29(4): 1027-1043.
[4]Okahara M, Kiyosue H, Mori H, et al. Anatomic variations of the cerebral arteries and their embryology: a pictorial review[J]. Eur Radiol, 2002, 12(10): 2548-2561.
[5]Krabbe-Hartkamp MJ, van der Grond J, de Leeuw FE, et al. Circle of Willis: morphologic variation on three-dimensional time-of-flight MR angiograms[J]. Radiology, 1998, 207(1): 103-111.
[6]Kovac JD, Stankovic A, Stankovic D, et al. Intracranial arterial variations: a comprehensive evaluation using CT angiography[J]. Med Sci Monit, 2014, 20: 420-427.
[7]van Raamt AF, Mali WP, van Laar PJ, et al. The fetal variant of the circle of Willis and its influence on the cerebral collateral circulation[J]. Cerebrovasc Dis, 2006, 22(4): 217-224.
[8]Padget DH. The development of the cranial arteries in the human embryo[J]. Contrib Embryol, 1948, 32: 205-261.
[9]van der Lugt A, Buter TC, Govaere F, et al. Accuracy of CT angiography in the assessment of a fetal origin of the posterior cerebral artery[J]. Eur Radiol, 2004, 14(9): 1627-1633.
[10]Wentland AL, Rowley HA, Vigen KK, et al. Fetal origin of the posterior cerebral artery produces left-right asymmetry on perfusion imaging[J]. Am J Neuroradiol, 2010, 31(3): 448-453.
[11]Horikoshi T, Akiyama I, Yamagata Z, et al. Magnetic resonance angiographic evidence of sex-linked variations in the circle of Willis and occurrence of cerebral aneurysms[J]. J Neurosurg, 2002, 96(4): 697-703.
[12]Hillen B, Hoogstraten HW, Van Overbeeke JJ, et al. Functional anatomy of the circulus arteriosus cerebri(Willis Ⅱ)[J]. Bull Assoc Anat(Nancy), 1991, 75(229): 123-126.
[13]叶莹莹，张伟国，陈蓉，等. 64层螺旋CTA显示胚胎型大脑后动脉伴发Willis环多血管段变异的价值[J].中国医学影像技术，2007，23（12）：1773-1776.
[14]Osborn AG. Diagnostic cerebral angiography[M]. 2nd ed. Philadeiphia: Lippincott Williams & Wilkins, 1999: 111.
[15]王洪生，徐新文，王辉，等. CT血管成像评价颅内Willis环变异与前后交通动脉动脉瘤发生的关系[J]. 中国脑血管病杂志，2011，8（12）：641-644.
[16]石建成，刘怀军，赵林，等. 脑血管形态学类型与脑动脉瘤形成相关性研究[J]. 实用放射学杂志，2010，26（10）：1401-1404.
[17]陈仁智，闫宏亮，薄晓霞，等. 双侧胚胎型大脑后动脉38例临床分析[J]. 中国医师进修杂志，2012，35（13）：43-45.
[18]Brinjikji W, Zhu YQ, Lanzino G, et al. Risk Factors for Growth of Intracranial Aneurysms: A Systematic Review and Meta-Analysis[J]. AJNR, 2016, 37(4): 615-620.
[19]Kang HG, Kim BJ, Lee J, et al. Risk Factors Associated With the Presence of Unruptured Intracranial Aneurysms[J]. Stroke, 2015, 46(11): 3093-3098.
[20]Jang EW, Kim YB, Chung J, et al. Clinical Risk Factors Affecting Procedure-Related Major Neurological Complications in Unruptured Intracranial Aneurysms[J]. Yonsei Med J, 2015, 56(4): 987-992.