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| The value of ultrasound in clinical diagnosis and treatment of Peutz-Jeghers syndrome |
| TIAN Qing, ZHU Hao-hui, YUAN Jian-jun, LI Hui |
| Department of Ultrasonography, Henan Provincial People’s Hospital, Zhengzhou 450003, China |
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Abstract Objective: The aim of this paper was to improve the awareness of sonographers to characteristics of polyps and secondary changes of Peutz-Jeghers syndrome(PJS). Methods: A retrospective analysis was made to the ultrasound, clinical data and postoperative pathologies of 6 cases of PJS in our hospital from February 2012 to April 2016. Results: Six cases of polyps caused by PJS and 3 cases of intussusception caused by polyps were found in the small intestine by ultrasound compared with the findings during the operations. Conclusions: Ultrasound is a more effective means for the diagnosis of polyps caused by PJS, because it can evaluate the polyp characters, observe intussusception and intestinal obstruction caused by polyps, assess the overall situation in the abdomen. Ultrasound provides a reliable basis for clinical diagnosis and treatment for its simple, non-invasive and real-time.
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Received: 27 February 2017
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[1]Utsunomiya J, Gocho H, Miyanaga T, et al. Peutz-Jeghers syndrome: its natural course and management[J]. Johns Hopkins Med J, 1975, 136(2): 71-82.
[2]刘虹，赵阳． Ｂ超诊断黑斑息肉病１例报告[J]． 宁夏医学杂志，1996，18（5）：300．
[3]王子干． 超声诊断Peutz-Jeghers综合征并发小肠５处套叠１例[J]． 中国超声医学杂志，1999，15（3）：237．
[4]薛燕，刘钮狰． 黑斑息肉病超声表现１例[J]． 中华超声影像学杂志，2005，14（4）：278．
[5]腾华，魏鑫，李静． 彩色多普勒超声诊断Peutz-Jeghers氏综合征并肠套叠１例[J]． 医学影像学杂志，2006，16（6）：556．
[6]王晓，吴争勇． 黑斑息肉综合征并发多发性肠套叠超声表现１例[J]． 临床超声医学杂志，2007，9（3）：178．
[7]毛旭燕，宁守斌. Peutz-jeghers综合征发病机制和诊疗进展[J]. 胃肠病学，2014，19（8）：492-495.
[8]Kang S, Kim ES, Moon A. Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras[J]. Oneol Rep, 2009, 21(5): 1317-1322.
[9]Van Lier MG, Mathus-Vliegen EM, Wagner A, et al. High cumulative risk of intussusception in patients with Peutz-Jeghers syndrome: time to update surveillance guidelines？[J]. Am J Gastroenterol, 2011, 106(5): 940-945.
[10]唐琪，周平，陈晓，等． Peutz-Jeghers综合征肠套叠的累积危险度与临床特征[J]． 中华消化杂志，2014，34（2）：118-120．
[11]Whitelaw SC, Murday VA, Tomlinson IP, et al. Clinical and molecular features of the hereditary mixed polyposis syndrome[J]. Gastroenterology, 1997, 112(2): 327-334.
[12]Wu TT, Rezai B, Rashid A, et al. Genetic alterations and epithelial dysplasia in juvenile polyposis syndrome and sporadic juvenile polyps[J]. Am J Pathol, 1997, 150(3): 939-947.
[13]康素海，程广河，李改兰，等. 黑斑-胃肠道息肉综合征息肉恶变途径分析[J]. 中华临床医师杂志：电子版，2015，10（9）：3498-3502.
[14]戴益琛，宋于刚，肖冰，等. 黑斑息肉综合征临床病理研究52例[J]. 武警医学，2008，19（5）：450-452. |
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