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The differential diagnosis of pelvic lymph nodes with high FDG uptake in early-stage cervical carcinoma using 18F-FDG PET/CT |
SUI Shi, XIN Jun |
Department of Nuclear Medicine, Shengjing Hospital of China Medical University, Shenyang 110004, China |
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Abstract Objective: To differentiate the pelvic lymph nodes with high FDG uptake in early-stage cervical carcinoma using 18F-FDG PET/CT imaging. Methods: Fifty-three cases with FDG avid primary lesions and pelvic lymph nodes were retrospectively analyzed. Short axis, SUVmax, SUVmean, MTV and TLG of the lymph nodes were compared between the metastasis group and non-metastasis group. The diagnostic efficacies of statistically significant parameters were calculated and compared. Results: Seventy-six 18F-FDG high-uptake lymph nodes were included in the following analysis. All the 5 parameters mentioned above were statistically different(P<0.05). The AUCs of short axis, SUVmax, SUVmean, MTV and TLG were 0.76, 0.87, 0.86, 0.67, 0.79, while their sensitivity and specificity were 60.61%, 75.76%, 72.73%, 54.55%, 66.67%, and 86.05%, 88.37%,88.37%, 76.74%, 81.40% respectively. Statistical difference existed between ROCs of SUVmax and short axis, MTV, as well as TLG, while the difference was also confirmed between SUVmean and MTV, MTV and TLG(P<0.05). Conclusion: 18F-FDG PET/CT is useful in differentiating pelvic lymph nodes with high FDG uptake in early-stage cervical carcinoma. SUVmax and SUVmean can be promising parameters.PET/CT
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Received: 26 August 2016
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