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Preliminary application of dual-energy dual-source CT virtual non-contrast imaging in#br# inflammatory bowel diseases |
LAN Xing1, TANG Hao2, ZHOU Fan3, ZHOU Chang-sheng2, HUANG Wei2 |
(1.School of Medical Imaging, Xuzhou Medical University, Xuzhou Jiangsu 221004, China;
2.Department of Medical Imaging, Jinling Hospital, Nanjing 210002, China;
3.Nanjing Drum Tower Hospital Affiliated with Medical School of Nanjing University, Nanjing 210008, China) |
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Abstract Objective: To assess the clinical feasibility of dual-source CT enterography using dual-energy virtual non-contrast(VNCT) imaging in diagnosis of inflammatory bowel diseases. Materials and Methods: The dual-energy dual-source CT enterography data from a cohort of 37 inflammatory bowel disease patients(31 Crohn’s disease and 6 ulcerative colitis), who were confirmed by clinical settings, were analyzed retrospectively. All the patients underwent abdominal conventional non-enhanced CT scan(CNCT) as well as arterial and venous phase dual-energy enhanced scan(100 kVp/210 mAs and Sn140 kVp/162 mAs). VNCT images of arterial and venous phase were obtained using the dual-energy software. The differences of image quality, radiation dose and diagnostic coincidence rate between the true non-contrast scan and VNC images were compared. Results: Compared with CNCT images, all the inflammatory bowel segments were detected accurately by VNCT images, and there was no significant difference of size and extent of lesions between the CNCT and VNCT. All the VNCT images met the requirement of diagnosis, and the differences of intestinal wall thickness, intestinal wall edema or effusion, intestinal morphology and lymph node size were no significant. The noise level of images obtained from VNC was lower than that of the real non-contrast scan(P<0.05), with higher SNR(P<0.05). There was no significant difference of image scoring among the three groups(P>0.05). There was no statistic difference of the radiation dose of conventional non-enhanced CT, arterial and venous phase CECT. The radiation dose of two-phase dual-energy scan was 32.97% lower than that of the conventional threephase scans. Conclusion: For inflammatory bowel diseases, the virtual non-contrast images obtained from the dual-energy CT scan can effectively reduce the radiation dose, decrease radiation injury, and meet the needs of clinical diagnosis.
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Received: 19 August 2016
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[1]耿小川, 许建荣. 炎症性肠病影像学诊断的现状和展望 [J]. 中华临床医师杂志:电子版,2013,7(23):10390-10395.
[2]Kaufmann S, Sauter A, Spira D, et al. Tin-filter enhanced dual-energy-CT: image quality and accuracy of CT numbers in virtual noncontrast imaging[J]. Acad Radiol, 2013, 20(5): 596-603.
[3]Sahni V, Shinagare A, Silverman S. Virtual unenhanced CT images acquired from dual-energy CT urography: accuracy of attenuation values and variation with contrast material phase[J]. Clin Radiol, 2013, 68(3): 264-271.
[4]张龙江,卢光明. 双能量CT的技术原理及在腹部的应用[J]. 国际医学放射学杂志,2010,33(2):118-121.
[5]Tsapaki V, Kottou S, Papadimitriou D. Application of European Commission reference dose levels in CT examinations in Crete, Greece[J]. Br J Radiol, 2001, 74(885): 836-840.
[6]Chatu S, Subramanian V, Pollok RCG. Meta-analysis: diagnostic medical radiation exposure in inflammatory bowel disease[J]. Alimentary Pharmacology Therapeutics, 2012, 35(5): 529-539.
[7]章士正. 小肠影像检查的方法及应用选择[J]. 中华放射学杂志,2012,46(4):298-299.
[8]田士峰,刘爱连. 双能CT虚拟平扫进展及临床应用[J]. 国际医学放射学杂志,2014,37(1):54-57.
[9]Godoy MC, Naidich DP, Marchiori E, et al. Single-acquisition dual-energy multidetector computed tomography: analysis of vascular enhancement and postprocessing techniques for evaluating the thoracic aorta[J]. J Comput Assisted Tomogr, 2010, 34(5): 670-677.
[10]Marin D, Nelson RC, Samei E, et al. Hypervascular liver tumors: low tube voltage, high tube current multidetector CT during late hepatic arterial phase for detection—initial clinical experience[J]. Radiology, 2009, 251(3): 771-779.
[11]Zhang LJ, Peng J, Wu SY, et al. Liver virtual non-enhanced CT with dual-source, dual-energy CT: a preliminary study[J]. Eur Radiol, 2010, 20(9): 2257-2264.
[12]汪田田,李剑,任静,等. 双源CT双能量虚拟平扫在腹部应用的可行性研究[J]. 实用放射学杂志,2013,29(3):446-465.
[13]邓丽萍,史晓喆,章士正,等. 双源CT小肠造影双能量虚拟平扫的临床评估[J]. 放射学实践,2014,29(12):1439-1442.
[14]王勇,雷静,韩丹,等. 双源CT双能量虚拟平扫在结直肠病变的应用[J]. 中国医学影像学杂志,2014,22(10):768-771.
[15]杨丽,时高峰,吴润泽,等. 第二代双源CT虚拟平扫对胃癌浆膜面脂肪显示能力的评估[J]. 实用放射学杂志,2014,30(6):947-950. |
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