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| Values of seven joint semi-quantitative ultrasonic score in rheumatoid arthritis curative effect monitoring |
| YE Jing-jing, HUANG Xiao-min, LI Yu-sheng |
| Department of Ultrasound, Ningde Hospital Affiliated to Fujian Medical University, Ningde Fujian 352100, China |
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Abstract Objective: To explore the value of the seven joint semi-quantitative ultrasonic score in rheumatoid arthritis(RA) curative effect monitoring. Methods: Sixty-two patients with RA were involved in this study. Anti-CCP, RF, ESR, CRP and DAS28 were examined at the start point, 3 and 6 months after treatment of disease-modifying anti-rheumatic drugs. The patients’s wrist, the second and third metacarpophalangeal joints, the second and third proximal interphalangeal joints, and the second and fifth metatarsophalangeal joints were examined by high frequency ultrasound. Synovitis, tenosynovitis and bone erosion were graded by grey scale ultrasound(GSUS) and power Doppler ultrasound(PSUS). The correlation between the semi-quantitative ultrasound score and the DAS28 score and the activity indicators were analyzed. Results: Six months after treatment, DAS28, Anti-CCP, RF, ESR, and CRP decreased significantly. Values of synovitis GSUS, synovitis PDUS, tenosynovitis GSUS and tenosynovitis PDUS also decreased. There was significant difference(P＜0.01). The change of bone erosion score was not obvious before and after treatment. There was no statistical difference(P>0.05). Three and six months after treatment, there were positive correlations between synovitis GSUS, synovitis PDUS, tenosynovitis GSUS, tenosynovitis PDUS and DAS28, ESR, CRP(P<0.01). There was no correlation between bone erosion score and DAS28, Anti-CCP, RF, ESR and CRP(P>0.05). Conclusion: The seven joint semi-quantitative ultrasonic score has a good correlation with the clinical and serological indicators. It is an important method to monitor the curative effect of RA.
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Received: 14 March 2018
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