分化型甲状腺癌术后患者首次131I “清甲”治疗后对唾液腺功能的影响

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Abstract Objective: To study the changes of salivary gland function in patients with differentiated thyroid carcinoma(DTC) who underwent high dose 131I ablative therapy for the first time. Methods: 53 patients with DTC were treated with 3.7 GBq of 131I. Salivary gland dynamic imaging was performed 1 week before treatment and 3 months after treatment. Results: There was no significant difference in salivary gland uptake between before and after iodine treatment in the 53 patients with DTC(P>0.05), but the excretory function was significantly lower after treatment than that before(P<0.05). Of 53 patients, 14 cases(26.41%) were with dry mouth symptoms or aggravated dry mouth symptoms. There was no significant difference in salivary gland uptake function between the 14 patients before and after treatment(P>0.05), but the excretory function was markedly reduced after treatment(P<0.05). Conclusion: The salivary gland uptake function was normal 3 months after the first high dose 131I ablative treatment. But the excretion function was significantly impaired.

Key words： Thyroid neoplasms Salivation Radionuclide imaging

Received: 15 August 2017

PACS:	Ｒ736.1
	Ｒ817.4

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	Articles by authors
	YANG Wen-ding
	ZOU Jin-tao
	QIN Wei-hua
	QIN Shao-chao
	DONG Jing-wei

Cite this article:

YANG Wen-ding,ZOU Jin-tao,QIN Wei-hua, et al. Effects of first 131I treatment on salivary gland function in patients with differentiated thyroid carcinoma[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(5): 313-315.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I5/313

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