高频超声评价2型糖尿病患者股动脉血管重构及其#br#
与中性粒细胞/淋巴细胞比值的相关性

doi:10.12117/jccmi.2018.09.007

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To evaluate remodeling of the femoral artery and its correlation with neutrophil to lymphocyte ratio(NLR) in patients of type 2 diabetes mellitus(T2DM) by high-frequency ultrasound. Methods: Eighty-eight patients with T2DM were divided into group B(48 cases, the course≤10 years) and group C(40 cases, the course>10 years). 36 healthy volunteers were recruited as the control group(group A). The intimal medial thickness(IMT), total vessel area(TVA), lumen area(LA) were measured and vascular remodeling types were determined. NLR was calculated and obtained from the peripheral blood routine examination.　Results: IMT and NLR of the femoral in group B and C were higher, has significant difference. And IMT and NLR of the femoral in group C were higher than that in group B(all P<0.05). RI in group B was higher than that of group A (P<0.05). RI in group C was lower than that of group B(P<0.05). The vascular remodeling rates in group B and C were higher than that in group A(all P<0.05), and in group C was higher than that in group B(P<0.05). The positive remodeling rate of group B was higher than that of other two groups, and the difference were significant. The rate of negative remodeling in group C was higher than that of group A and B(all P<0.05). Vessels without remodeling was predominant in group A. The rate of negative remodeling was higher than the rate of positive remodeling in group C. The rate of positive remodeling was higher than the rate of negative remodeling in group B. IMT was positively correlative with NLR(r=0.56, P<0.05). Conclusion: The atherosclerosis, vascular remodeling of the femoral artery and the relationship with NLR in the patients of T2DM can be evaluated conveniently and accurately by high-frequency ultrasonography with an important clinical value.

Key words： Arteriosclerosis Diabetes mellitus, type 2 Ultrasonography, Doppler, color

Received: 02 November 2017

PACS:	Ｒ543.5
	Ｒ445.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	DING A-na
	ZHANG Yu-hong
	SU Ben-li

Cite this article:

DING A-na,ZHANG Yu-hong,SU Ben-li. Evaluation of remodeling of femoral artery and its correlation with neutrophil to lymphocyte ratio in#br# patients of type 2 diabetes mellitus by high-frequency ultrasonography[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(9): 633-635.

URL:

http://www.jccmi.com.cn/EN/10.12117/jccmi.2018.09.007 OR http://www.jccmi.com.cn/EN/Y2018/V29/I9/633

[1]Park BJ, Shim JY, Lee HR, et al. Relationship of neutrophil lymphocyte ratio with arterial stiffness and coronary calcium score[J]. Clin Chim Acta, 2011, 12(412): 925-929.
[2]Matsumura T, Taketa K, Motoshima H, et al. Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes[J]. Cardiovasc Diabetol, 2013, 12(177): 1-10.
[3]张伟，吴海燕，张慧琴，等. 超声评价2型糖尿病患者股动脉内中膜厚度的临床研究[J]. 临床超声医学杂志，2012，14（9）：647-648.
[4]徐智章，张爱宏. 外周血管超声彩色血流成像[M]. 北京：人民卫生出版社，2002：95-96.
[5]罗淑荣，梁振茹，于英俊，等. 糖尿病患者颈动脉、股动脉超声检查[J]. 中国医学影像技术，2002，18（3）：231-232.
[6]张梅，张运，戴晓华，等. 颈动脉粥样硬化血管重构及其后效影响因素的研究[J]. 中国超声医学杂志，2003，19（5）：334-336.
[7]Libby P. Inflammation in atherosclerosis[J]. Arterioscler Thromb Vasc Biol, 2012, 32(9): 2045-2051.
[8]Akil E, Akil MA, Varol S, et al. Echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio are novel inflammatory predictors of cerebral ischemic stroke[J]. J Stroke Cerebrovasc Dis, 2014, 23(9): 2328-2334.
[9]吴凤芸，张宇虹，苏本利. 高频超声评价2型糖尿病患者颈动脉粥样硬化血管重构[J]. 中国医学影像技术，2009，25（1）：65-68.
[10]耿纪录，杨子姜，戴富林. 糖尿病血管重构及其防治[J]. 天津医药，2000，28（1）：62-64.
[11]高月花，张梅，张运，等. 颈动脉粥样硬化与股动脉粥样硬化的比较[J]. 医学影像学杂志，2010，20（11）：1006-1011.
[12]姚智，杨艳秋，张芙荣，等. 颈动脉和股动脉粥样硬化与血流动力学、血管内皮功能的关系[J]. 陕西医学杂志，2010，39（8）：1000-7377.
[13]Tamhane UU, Aneja S, Montgomery D, et al. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome[J]. Am J Cardiol, 2008, 102(6): 653-657.
[14]姜红，吴舰，魏光如. 中性粒细胞淋巴细胞比值与颅外颈动脉狭窄的相关性研究[J]. 中华老年心脑血管病杂志，2016，18（1）：55-58.
[15]Soehnlein O. Multiple roles for neutrophils in atherosclerosis[J]. Circ Res, 2012, 110(6): 875-888.
[16]Huang YL, Chung HT, Chang CJ, et al. Lymphopenia is a risk factor in the progression of carotid intima-media thickness in juvenile-onset systemic lupus erythematosus[J]. Arthritis Rheum, 2009, 60(12): 3766-3775.